Efficacy and Safety of Nipent, Cytoxan and Rituxan in the Treatment of Chronic Lymphocytic Leukemia.
Chronic Lymphocytic Leukemia
About this trial
This is an interventional treatment trial for Chronic Lymphocytic Leukemia focused on measuring Leukemia, Cancer, Nipent, Rituxan, Cytoxan
Eligibility Criteria
Inclusion Criteria: Stage II, III or IV Chronic Lymphocytic Leukemia Disease requires chemotherapeutic treatment CT or MRI scan confirming measurable tumor size Documentation of CD markers Up to one prior treatment regimen Expected survival greater than 6 months ECOG performance status of 0-2 Adequate renal, bone marrow and liver functions Negative pregnancy test (females of childbearing potential) Must agree to use acceptable birth control, if fertile Must complete Informed Consent No heart disease and must have adequate cardiac function Must test negative for viral Hepatitis B and C Exclusion Criteria: More than one prior treatment for Chronic Lymphocytic Leukemia Known sensitivity to Nipent, Rituxan or Cytoxan or any component of these drugs Known HIV or AIDS illness Thyroid disease requiring medication History of any malignancy that could affect the diagnosis or assessment of the study treatment Pregnancy or breast feeding Evidence of Hepatitis B or C infection Inability to comply with the requirements of the study
Sites / Locations
- Northwest Alabama Cancer Center, PCRecruiting
- East Valley Hematology and Oncology Medical GroupRecruiting
- Bay Area Cancer Research GroupRecruiting
- Lalita Pandit, MD, Inc.Recruiting
- Pacific Coast Hematology/Oncology Medical Group, Inc.Recruiting
- Robert A. Moss, M.D. FACP, Inc.Recruiting
- Metropolitan Hematology Oncology Medical GroupRecruiting
- North County OncologyRecruiting
- Ventura County Hematology Oncology SpecialistsRecruiting
- Cancer and Blood Institute Medical GroupRecruiting
- St. Teresa Comprehensive Cancer CenterRecruiting
- Medical Group of North CountyRecruiting
- The Oncology Clinic, PCRecruiting
- Mile High OncologyRecruiting
- Palm Beach Institute of Hematology and OncologyRecruiting
- Integrated Community Oncology NetworkRecruiting
- Osceola Cancer CenterRecruiting
- Pasco Hernando Oncology Associates, PARecruiting
- Pasco Pinellas Cancer CenterRecruiting
- Augusta Oncology Associates, PCRecruiting
- Spalding Oncology ServicesRecruiting
- St Luke's Mountain States Tumor InstituteRecruiting
- Oncology Hematology Assoc. of Northern IllinoisRecruiting
- Indiana Oncology Hematology ConsultantsRecruiting
- Arnett Cancer CareRecruiting
- Cancer Care CenterRecruiting
- Kentucky Cancer ClinicRecruiting
- Greater Baltimore Medical CenterRecruiting
- Chesapeake Oncology Hematology AssociatesRecruiting
- Auerbach Hematology Oncology Associates, Inc.Recruiting
- Genesee Cancer & Blood Disease Treatment Center, PCRecruiting
- West Michigan Regional Cancer & Blood CenterRecruiting
- Spectrum Health HospitalsRecruiting
- Branson Oncology ClinicRecruiting
- St. Louis Hematology Oncology Specialists, Inc.Recruiting
- Sierra Nevada Oncology CareRecruiting
- Nevada Cancer CenterRecruiting
- The Center for Cancer and Hematologic DiseaseRecruiting
- Ellioth Fishkin, MDRecruiting
- Westchester Hematology Oncology AssociatesRecruiting
- Mid Dakota Clinic/Odyssey ResearchRecruiting
- Summa Health System HospitalsRecruiting
- Nashat Y. Gabrail, MD, Inc.Recruiting
- Sambandam and Joseph Associates, IncRecruiting
- Charleston Hematology Oncology, PARecruiting
- South Carolina Oncology AssociatesRecruiting
- The Family Cancer CenterRecruiting
- C. Michael Jones, MD, PCRecruiting
- JPS Center for Cancer CareRecruiting
- Cache Valley Cancer Treatment & Research Clinic, Inc.Recruiting
- Cancer Outreach Associates, PCRecruiting
- Virginia Oncology Care, PCRecruiting