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Biomechanical Parameters of Gait in Patients With Parkinson's Disease and Parkinsonian Syndromes

Primary Purpose

Gait Disorders, Neurologic

Status

Terminated

Phase

Not Applicable

Locations

France

Study Type

Interventional

Intervention

Force platform and electromyography

About this trial

This is an interventional diagnostic trial for Gait Disorders, Neurologic focused on measuring Gait disorders, Postural instability, parkinsonian syndrome, Gait initiation, Parkinson's disease, Adults

Eligibility Criteria

18 Years - 85 Years (Adult, Older Adult)All SexesAccepts Healthy Volunteers

Inclusion Criteria: Patients able to walk without assistance Patients with Parkinson's disease or other degenerative parkinsonian syndromes (progressive supranuclear palsy [PSP], multiple system atrophy [MSA], corticobasal degeneration [CBD], etc.) Exclusion Criteria: Other parkinsonian syndromes Dementia Neuroleptic treatment

Sites / Locations

Centre d'Investigation Clinique-Hôpital Pitié-Salpetriere

Outcomes

Primary Outcome Measures

Biomechanical gait initiation parameters

Secondary Outcome Measures

Full Information

NCT ID

NCT00139321

First Posted

August 30, 2005

Last Updated

January 7, 2013

Sponsor

Groupe Hospitalier Pitie-Salpetriere

Collaborators

Institut National de la Santé Et de la Recherche Médicale, France

1. Study Identification

Unique Protocol Identification Number

NCT00139321

Brief Title

Biomechanical Parameters of Gait in Patients With Parkinson's Disease and Parkinsonian Syndromes

Official Title

Biomechanical Parameters of Gait in Patients With Parkinson's Disease and Parkinsonian Syndromes

Study Type

Interventional

2. Study Status

Record Verification Date

January 2013

Overall Recruitment Status

Terminated

Study Start Date

June 2004 (undefined)

Primary Completion Date

July 2007 (Actual)

Study Completion Date

July 2007 (Actual)

3. Sponsor/Collaborators

Responsible Party, by Official Title

Principal Investigator

Name of the Sponsor

Groupe Hospitalier Pitie-Salpetriere

Collaborators

Institut National de la Santé Et de la Recherche Médicale, France

4. Oversight

5. Study Description

Brief Summary

Gait disorders and falls are frequent in patients with parkinsonian syndromes. In patients with Parkinson's disease (PD), these signs occurred later during the course of the disease in comparison to patients with other degenerative parkinsonian disorders. The pathophysiology of these symptoms are still not fully understood. Gait initiation challenges the balance control system as the body moves from an upright stable static posture to a continuously unstable gait. The aim of this study is to analyse the gait initiation process in patients with parkinsonian disorders.

6. Conditions and Keywords

Primary Disease or Condition Being Studied in the Trial, or the Focus of the Study

Gait Disorders, Neurologic

Keywords

Gait disorders, Postural instability, parkinsonian syndrome, Gait initiation, Parkinson's disease, Adults

7. Study Design

Primary Purpose

Diagnostic

Study Phase

Not Applicable

Interventional Study Model

Single Group Assignment

Masking

None (Open Label)

Allocation

Non-Randomized

Enrollment

110 (Anticipated)

8. Arms, Groups, and Interventions

Intervention Type

Device

Intervention Name(s)

Force platform and electromyography

Primary Outcome Measure Information:

Title

Biomechanical gait initiation parameters

10. Eligibility

Sex

All

Minimum Age & Unit of Time

18 Years

Maximum Age & Unit of Time

85 Years

Accepts Healthy Volunteers

Eligibility Criteria

Overall Study Officials:

First Name & Middle Initial & Last Name & Degree

Yves Agid, MD, PhD

Organizational Affiliation

CIC-Pitié-Salpêtrière

Official's Role

Study Director

Facility Information:

Facility Name

Centre d'Investigation Clinique-Hôpital Pitié-Salpetriere

City

Paris

ZIP/Postal Code

75013

Country

France

12. IPD Sharing Statement

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Biomechanical Parameters of Gait in Patients With Parkinson's Disease and Parkinsonian Syndromes

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