Pneumonia Vaccine in Bone Marrow Transplant Recipients: Usefulness of Donor Vaccination
Bone Marrow Transplant
About this trial
This is an interventional prevention trial for Bone Marrow Transplant focused on measuring Bone Marrow Transplant, Pneumonia, Vaccine, Conjugate Vaccine, Polysaccharide Vaccine
Eligibility Criteria
Inclusion Criteria: Recipient - Adult male or female marrow recipients who fulfill the following criteria will be eligible for the study: a) Will undergo allogeneic-HSCT in 2-3 weeks. b) No splenectomy c) Not currently receiving IVIG d) Able to provide written informed consent and comply with study protocol e) Age > 16 Donor - Adult male or female marrow donors who fulfill the following criteria will be eligible for the study: Recipient of donor marrow agrees to participate in study. No prior pneumococcal vaccination within the last 5 years Not on immunosuppressive medication (eg., corticosteroids) No history of immunosuppressive condition that may potentially impair vaccine response eg, systemic lupus erythematosus, sarcoidosis, rheumatoid arthritis No splenectomy Able to provide written informed consent and comply with study protocol Age > 16
Sites / Locations
- University Health Network-Princess Margaret Hospital