Gene Expression During Chemotherapy in Patients With Newly Diagnosed Acute Myeloid Leukemia Treated With Choline Magnesium Trisalicylate

DISEASE CHARACTERISTICS: Histologically confirmed acute myeloid leukemia Newly diagnosed disease Presence of cytogenetic abnormalities must be determined by standard cytogenetics with or without FISH studies Leukemic blast count > 5,000/mm³ of peripheral blood No acute promyelocytic leukemia (M3) PATIENT CHARACTERISTICS: ECOG performance status 0-3 Bilirubin < 2.0 times upper limit of normal (ULN) AST < 3.0 times ULN Creatinine < 1.5 times ULN Not pregnant or nursing Negative pregnancy test Fertile patients must use effective contraception No uncontrolled psychiatric illness that, in the opinion of the principal investigator, would preclude study compliance No other concurrent medical condition that would preclude study compliance No allergies to any investigational drugs and/or chemotherapeutic agents No upper or lower gastrointestinal (GI) related hemorrhage within the past 6 months as determined by endoscopy No clinical diagnosis of GI bleeding requiring blood transfusions PRIOR CONCURRENT THERAPY: No prior induction therapy No prior chemotherapy for acute leukemia No concurrent medications that would preclude study compliance