Prodrome-Based Early Intervention With Antipsychotics vs. Benzodiazepines in First-Episode Schizophrenia
Schizophrenia, Psychoses
About this trial
This is an interventional treatment trial for Schizophrenia focused on measuring Schizophrenia, first episode, prodrome based early intervention, antipsychotics - benzodiazepine, maintenance treatment, drug discontinuation
Eligibility Criteria
Inclusion Criteria: First-episode in schizophrenia (according ICD-10 F20) Age between 18 and 55 Informed consent One year neuroleptic maintenance treatment Exclusion Criteria: Residence outside of the catchment area Legal reasons Insufficient knowledge of the german language Substance abuse or addiction Pregnancy Serious physical illness Organic brain disease Contraindication to neuroleptic treatment
Sites / Locations
- German Research Network on Schizophrenia, Department of Psychiatry and Psychotherapy at the Heinrich-Heine-University Düsseldorf
Arms of the Study
Arm 1
Arm 2
Experimental
Active Comparator
1
2
Early intervention with benzodiazepines in case of prodromal symptoms of an impending relapse
Early intervention with antipsychotics in case of prodromal symptoms of an impending relapse