Role of Doppler Ultrasound in Severe Peptic Ulcer Hemorrhage
Peptic Ulcer Hemorrhage
About this trial
This is an interventional treatment trial for Peptic Ulcer Hemorrhage focused on measuring Peptic ulcer hemorrhage, Doppler ultrasound
Eligibility Criteria
Inclusion Criteria: Clean base ulcer with severe upper GIB (defined as melaena, hematochezia, hematemesis, and/or gross blood in NG lavage), and any one of the following: SBP ≤ 90mmHg; P of ≥110 bpm; or orthostatic changes with SBP drops 20mmHg or P increases 20 bpm; or, Transfusion of 2 or more units of packed red blood cells within 12 hrs of admission; or, A documented HCT drop of at lest 6% from baseline. Endoscopically confirmed bleeding from GU, DU, pyloric ulcer, or anastomotic ulcer Pt can either have primary or secondary acute UGI haemorrhage Exclusion Criteria: Bleeding site from lesion other than GU, DU, pyloric or anastomotic ulcer there is more than one type of significant bleeding lesion Documented hx of cirrhosis / portal HT ESRF requiring any form of dialysis Expected or persistent (>24hrs) coagulopathy with INR> 1.5 Platelet count is under 50000/mm3 Aspirin User / Plavix [Clopidogrel] User If the ulcer is neoplastic Cannot obtained consent Age < 18 or is pregnant Severe comorbid of which life expectancy <30 days
Sites / Locations
- Endoscopy Center, Prince of Wales Hospital
Arms of the Study
Arm 1
Arm 2
Active Comparator
No Intervention
Doppler ultrasound
No Doppler ultrasound