Prevention and Treatment of Hemodialysis Vascular Access Malfunction
End-Stage Renal Disease
About this trial
This is an interventional treatment trial for End-Stage Renal Disease focused on measuring End Stage Renal Disease, ESRD, Chronic Maintenance Hemodialysis
Eligibility Criteria
Inclusion Criteria: Subjects with End Stage Renal Disease on chronic maintenance hemodialysis 3 times per week Have an arteriovenous (polytetrafluoroethylene) graft as vascular access Have a venous stenosis between 30% and 70% as determined by angiogram Exclusion Criteria: Native arteriovenous fistula Known previous vascular accesses complications, such as central vein stenosis, and multiple access surgeries >4 Unwilling to participate Allergy to iodine Absolute contraindication for surgery (e.g. medical condition precludes anesthesia and surgery) Known arterial limb stenosis or long vessel length venous stenosis which are unamenable to surgical or angioplasty techniques, respectively, and therefore prohibit randomization Known hypercoagulable state
Sites / Locations
- Vanderbilt University Medical Center
Arms of the Study
Arm 1
Arm 2
Arm 3
No Intervention
Active Comparator
Active Comparator
1
2
3
control group
angioplasty intervention
surgery intervention