Preventing Depression Relapse With Mindfulness-Based Cognitive Therapy
Depression
About this trial
This is an interventional prevention trial for Depression focused on measuring Depression Recurrence, Drug Therapy, Cognitive Therapy, Relapse, Antidepressants
Eligibility Criteria
Inclusion Criteria: Meet DSM criteria for recurrent major depressive disorder, defined as at least one major depressive episode within 3 years prior to study entry AND at least 2 months of normal functioning following the episode Exclusion Criteria: Depression secondary to a concurrent medical disorder Current use of medication that could cause depressive symptoms A rating of level 2 or higher on the Index of Treatment Refractory Depression Current diagnosis of any of the following psychiatric disorders: psychotic or organic mental, bipolar, primary obsessive compulsive, borderline personality, antisocial personality, or eating Current diagnosis of comorbid chronic depression that is disabling Current substance abuse Score less than 14 on the Hamilton Rating Scale for Depression-17 (HRSD-17) At risk for suicide Pregnancy or plan to become pregnant during the study Practice meditation more than once a week or yoga more than twice a week at study entry
Sites / Locations
- St. Joseph's Healthcare
- Centre for Addiction and Mental Health
Arms of the Study
Arm 1
Arm 2
Arm 3
Experimental
Active Comparator
Placebo Comparator
1
2
3
Participants will receive mindfulness based cognitive therapy
Participants will receive maintenance antidepressant pharmacotherapy
Participants will receive placebo plus clinical management