Maximal Leg Press Strength Training Study for Coronary Artery Disease Patients
Primary Purpose
Heart Failure, Coronary Artery Disease
Status
Completed
Phase
Not Applicable
Locations
Norway
Study Type
Interventional
Intervention
Strength training intervention
Sponsored by
About this trial
This is an interventional treatment trial for Heart Failure focused on measuring Cardiac heart failure, Leg press, Maximal strength training, Serum testosterone, Work economy
Eligibility Criteria
Inclusion Criteria: Clinically diagnosed coronary artery disease Stable coronary artery disease 1.5 mm depression in ST segment during a cycling strain test Between 18-70 years of age Exclusion Criteria: Unstable coronary artery disease Other limitations to exercise than coronary artery disease Participants in other study interventions
Sites / Locations
- Norwegian University of Science and Technology
Outcomes
Primary Outcome Measures
Maximal leg press strength
Work economy
Serum testosterone
Quality of life
Secondary Outcome Measures
Full Information
NCT ID
NCT00184457
First Posted
September 15, 2005
Last Updated
January 16, 2017
Sponsor
Norwegian University of Science and Technology
Collaborators
St. Olavs Hospital
1. Study Identification
Unique Protocol Identification Number
NCT00184457
Brief Title
Maximal Leg Press Strength Training Study for Coronary Artery Disease Patients
Official Title
Maximal Leg Press Strength Training for Coronary Artery Disease Patients. Training Effect on Serum Testosterone and Work Economy
Study Type
Interventional
2. Study Status
Record Verification Date
November 2011
Overall Recruitment Status
Completed
Study Start Date
September 2005 (undefined)
Primary Completion Date
April 2007 (Actual)
Study Completion Date
September 2007 (Actual)
3. Sponsor/Collaborators
Responsible Party, by Official Title
Sponsor
Name of the Sponsor
Norwegian University of Science and Technology
Collaborators
St. Olavs Hospital
4. Oversight
Data Monitoring Committee
No
5. Study Description
Brief Summary
Maximal strength training has been shown to increase muscular strength, muscular volume and work economy. An 8 week maximal leg press training regime will be conducted on cardiac heart failure patients to evaluate whether they increase their maximal leg press strength, work economy, serum testosterone and quality of life. The study hypotheses are that:
Aerobic work capacity will increase due to increased work economy, without increases in maximal oxygen uptake.
Strength training will increase serum testosterone.
6. Conditions and Keywords
Primary Disease or Condition Being Studied in the Trial, or the Focus of the Study
Heart Failure, Coronary Artery Disease
Keywords
Cardiac heart failure, Leg press, Maximal strength training, Serum testosterone, Work economy
7. Study Design
Primary Purpose
Treatment
Study Phase
Not Applicable
Interventional Study Model
Single Group Assignment
Masking
None (Open Label)
Allocation
Non-Randomized
Enrollment
12 (Actual)
8. Arms, Groups, and Interventions
Intervention Type
Behavioral
Intervention Name(s)
Strength training intervention
Primary Outcome Measure Information:
Title
Maximal leg press strength
Title
Work economy
Title
Serum testosterone
Title
Quality of life
10. Eligibility
Sex
All
Minimum Age & Unit of Time
18 Years
Maximum Age & Unit of Time
70 Years
Accepts Healthy Volunteers
No
Eligibility Criteria
Inclusion Criteria:
Clinically diagnosed coronary artery disease
Stable coronary artery disease
1.5 mm depression in ST segment during a cycling strain test
Between 18-70 years of age
Exclusion Criteria:
Unstable coronary artery disease
Other limitations to exercise than coronary artery disease
Participants in other study interventions
Overall Study Officials:
First Name & Middle Initial & Last Name & Degree
Asbjørn Støylen, MD
Organizational Affiliation
Norwegian University of Science and Technology
Official's Role
Study Director
Facility Information:
Facility Name
Norwegian University of Science and Technology
City
Trondheim
ZIP/Postal Code
7489
Country
Norway
12. IPD Sharing Statement
Citations:
PubMed Identifier
19199203
Citation
Karlsen T, Helgerud J, Stoylen A, Lauritsen N, Hoff J. Maximal strength training restores walking mechanical efficiency in heart patients. Int J Sports Med. 2009 May;30(5):337-42. doi: 10.1055/s-0028-1105946. Epub 2009 Feb 6.
Results Reference
result
Learn more about this trial
Maximal Leg Press Strength Training Study for Coronary Artery Disease Patients
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