Response of Cardiac Resynchronization Therapy Optimization With Ventricle to Ventricle Timing in Heart Failure Patients
Heart Failure
About this trial
This is an interventional treatment trial for Heart Failure
Eligibility Criteria
Inclusion Criteria: Patient has a standard indication for a CRT-D. Patient has the ability to complete a 6-minute hall walk with the only limiting factor to be fatigue or shortness of breath. Patient is geographically stable and willing to comply with the required follow-up schedule. Prior to 1 month of randomization, patient's HF medications are maintained stable and remain stable throughout the study. Patients requiring a CRT-D replacement must comply with BOTH of the following: > 1 HF related hospitalization No class improvement or worsening in NYHA scale Exclusion Criteria: Patient's life expectancy is less than 12 months. Patient has had cardiac surgery within 6 months of enrollment. Patient has an epicardial ventricular lead system. Patient is less than 18 years old. Patient is pregnant.
Sites / Locations
- Ohio State University
Arms of the Study
Arm 1
Arm 2
Active Comparator
Active Comparator
Simultaneous VV Pacing
Sequential VV Pacing
Programmed to simultaneous biventricular pacing
Programmed to sequential biventricular pacing