Back to resultsMagnetic Resonance (MR) in Asthmatic Patients
Primary Purpose
Asthma
Status
Suspended
Phase
Phase 1
Locations
Canada
Study Type
Interventional
Intervention
magnetic resonance imaging (MRI) of the thorax
Sponsored by
About this trial
This is an interventional diagnostic trial for Asthma
Eligibility Criteria
Inclusion Criteria: All asthmatic patients are eligible. Exclusion Criteria: Patients in whom MRI is contraindicated
Sites / Locations
- Toronto General Hospital
Outcomes
Primary Outcome Measures
The correlation of MR lung perfusion analysis with computed tomography (CT) findings and pulmonary function tests
Secondary Outcome Measures
Full Information
NCT ID
NCT00188487
First Posted
September 12, 2005
Last Updated
April 20, 2007
Sponsor
University Health Network, Toronto
1. Study Identification
Unique Protocol Identification Number
NCT00188487
Brief Title
Magnetic Resonance (MR) in Asthmatic Patients
Official Title
MR Perfusion Imaging in Asthmatic Patients
Study Type
Interventional
2. Study Status
Record Verification Date
April 2007
Overall Recruitment Status
Suspended
Why Stopped
no funding
Study Start Date
September 2005 (undefined)
Primary Completion Date
undefined (undefined)
Study Completion Date
December 2005 (undefined)
3. Sponsor/Collaborators
Name of the Sponsor
University Health Network, Toronto
4. Oversight
5. Study Description
Brief Summary
Asthma is a disease of small airways. Affected areas have reduced lung ventilation causing reflex vasoconstriction. MR perfusion imaging of the lungs is a sensitive method of imaging zonal lung perfusion.
Detailed Description
A cohort of 70 Asthmatic Patients and 10 controls, both sets of subjects have HRCT, MRI/A of the Thorax, and Pulmonary Function Tests to correlate the degree of pulmonary dysfunction with findings on imaging tests.
6. Conditions and Keywords
Primary Disease or Condition Being Studied in the Trial, or the Focus of the Study
Asthma
7. Study Design
Primary Purpose
Diagnostic
Study Phase
Phase 1
Interventional Study Model
Single Group Assignment
Masking
None (Open Label)
Allocation
Non-Randomized
Enrollment
80 (false)
8. Arms, Groups, and Interventions
Intervention Type
Device
Intervention Name(s)
magnetic resonance imaging (MRI) of the thorax
Primary Outcome Measure Information:
Title
The correlation of MR lung perfusion analysis with computed tomography (CT) findings and pulmonary function tests
10. Eligibility
Sex
All
Minimum Age & Unit of Time
16 Years
Accepts Healthy Volunteers
Accepts Healthy Volunteers
Eligibility Criteria
Inclusion Criteria:
All asthmatic patients are eligible.
Exclusion Criteria:
Patients in whom MRI is contraindicated
Overall Study Officials:
First Name & Middle Initial & Last Name & Degree
Narinder Paul, FRCP C
Organizational Affiliation
University Health Network, Toronto
Official's Role
Principal Investigator
Facility Information:
Facility Name
Toronto General Hospital
City
Toronto
State/Province
Ontario
Country
Canada
12. IPD Sharing Statement
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Magnetic Resonance (MR) in Asthmatic Patients
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