Exhale (R) Stent for Emphysema
Emphysema
About this trial
This is an interventional treatment trial for Emphysema focused on measuring COPD (Chronic Obstructive Pulmonary Disease), Emphysema, Minimally invasive
Eligibility Criteria
Inclusion Criteria: High resolution computed tomography (CT) scan evidence of bilateral emphysema Residual volume (RV) ≥ 220% predicted. Total lung capacity (TLC) ≥ 133% of predicted value. Forced expiratory volume (FEV1) < 40% of predicted or FEV1 < 1 liter. Marked dyspnea, scoring ≥ 2 on the modified Medical Research Council scale of 0-4. Patient has undergone pulmonary rehabilitation of 16 - 20 sessions. Exclusion Criteria: FEV1 > 20% Diffusing capacity for carbon monoxide (DLco) < 15% of predicted. Respiratory infection requiring > 3 hospitalizations in past year Inability to walk > 140 meters in 6 minutes Giant bulla > 1/3 of one lung's volume Previous lung volume reduction surgery (LVRS) or lobectomy.
Sites / Locations
- The Prince Charles Hospital
- The Alfred Hospital
- Concord Repatriation General Hospital
- Irmandade Santa Casa de Misericordia
- Universitätsklinik des Saarlandes
- Medizinische Hochschule Hannover