Efficacy and Safety of Calcipotriol Plus Betamethasone Dipropionate Gel in Scalp Psoriasis
Psoriasis of Scalp
About this trial
This is an interventional treatment trial for Psoriasis of Scalp
Eligibility Criteria
Inclusion Criteria: Scalp psoriasis amenable to topical treatment with a maximum of 100 g of medication per week Clinical signs of psoriasis vulgaris on trunk and/or limbs, or earlier diagnosed with psoriasis vulgaris on trunk and/or limbs Extent of scalp psoriasis involving more than 10% of the total scalp area Investigator's assessment of clinical signs of the scalp of at least 2 in one of the clinical signs, erythema, thickness and scaliness, and at least 1 in each of the other two clinical signs Disease severity on the scalp graded as Mild, Moderate, Severe or Very severe according to the investigator's global assessment of disease severity Exclusion Criteria: PUVA or Grenz ray therapy within 4 weeks prior to randomisation UVB therapy within 2 weeks prior to randomisation Systemic treatment with biological therapies, with a possible effect on scalp psoriasis within 6 months prior to randomisation Systemic treatment with all other therapies than biologicals, with a possible effect on scalp psoriasis (e.g., corticosteroids, vitamin D analogues, retinoids, immunosuppressants) within 4 weeks prior to randomisation Any topical treatment of the scalp (except for medicated shampoos and emollients) within 2 weeks prior to randomisation Topical treatment of the face, trunk and/or limbs with very potent WHO group IV corticosteroids within 2 weeks prior to randomisation Current diagnosis of erythrodermic, exfoliative or pustular psoriasis
Sites / Locations
- Universitair Ziekenhuis Sint Rafaël, Dienst Dermatologie
- Innovaderm Research Inc.
- Policlinic of Dermatology, Medical Reception Centre
- Hôpital Trousseau, Service de Dermatologie CHU Tours
- Georg-August-Universität Göttingen, Abteilung Dermatologie und Venerologie
- Universitair Medisch, Centrum St. Radboud, Afdeling Dermatologie
- Royal Gwent Hospital, Department of Dermatology