Progesterone for the Treatment of Cocaine Dependence - 1
Cocaine Abuse, Cocaine-Related Disorders
About this trial
This is an interventional treatment trial for Cocaine Abuse focused on measuring Cocaine
Eligibility Criteria
Inclusion Criteria: Smoked at least 1 gram of cocaine each week for the 6 months prior to study entry Agrees to use an adequate method of contraception for the duration of the study If female, current regular menses Exclusion Criteria: Major psychiatric illnesses, including psychotic mood and anxiety disorders Current dependence on alcohol or drugs other that cocaine or nicotine History of major medical illnesses, including liver disease, abnormal vaginal bleeding, suspected or known breast cancer, thrombophlebitis, or other medical conditions Current use of oral contraceptives or other types of hormonal contraceptives Amenorrhea Currently on parole or probation Received treatment for chemical dependency within the 6 months prior to study entry Known allergy to progesterone or peanuts
Sites / Locations
- University of Minnesota
Arms of the Study
Arm 1
Arm 2
Active Comparator
Placebo Comparator
Progesterone
Placebo
200mg progesterone twice daily
Placebo twice daily