Intrathecal Baclofen Therapy and Paroxysmal Dysautonomia in Severe Brain-Injured Patients
Traumatic Brain Injury, Cerebral Anoxia, Coma
About this trial
This is an interventional treatment trial for Traumatic Brain Injury focused on measuring Severe brain injury, Coma, Hypertonia, Dysautonomia, Baclofen, Randomized Controlled Trials
Eligibility Criteria
Inclusion Criteria: severe brain injury with coma (Glasgow score <8) Early phase of recovery (spontaneous eye-opening) since at least one month and less than six months severe hypertonia of the lower limbs (mean Ashworth score >= 3) with neurovegetative episodes (at least 10 in 48 hours) and/or decortication after failure of treatment per os (clonidine, beta-blocker, baclofen per os) written informed consent (next of kin) Exclusion Criteria: surgical, anesthetic or allergic contraindication to baclofen uncontrolled sepsis directly threatening the implanted device associated medullary trauma
Sites / Locations
- Service de neurochirurgie B, Hôpital Pellergin Tripode