Effect of Paroxetine on COAT-Platelet Production in Normal Volunteers and Patients With Cardiovascular Disease
Coronary Artery Disease
About this trial
This is an interventional prevention trial for Coronary Artery Disease
Eligibility Criteria
Inclusion Criteria: normal volunteers (without heart disease) patients with heart disease between ages 18 & 65 Exclusion Criteria: children less than 18 years adults greater than 65 years those who can not keep appointments patients within 2 weeks of a coronary catheterization patients within 6 months of unstable angina or myocardial infarction individuals with allergies to paroxetine or similar medications individuals having adverse events to paroxetine or similar medications individuals with diagnosis of mania individuals with a diagnosis of hypomania individuals with a diagnosis of bipolar disorders individuals with a diagnosis of depression individuals with a diagnosis of panic disorders individuals with a diagnosis of seizure disorders individuals with a history of suicide attempts individuals with a diagnosis of hyponatremia individuals with active bleeding disorders individuals with a diagnosis of narrow angle glaucoma individuals with an estimated creatinine clearance of less that 30 ml/min individuals taking potentially interacting medications
Sites / Locations
- The University of Oklahoma Health Sciences Center