A Study of the Efficacy and Safety of Topiramate in the Prevention of Migraine
Migraine, Common Migraine, Classic Migraine
About this trial
This is an interventional treatment trial for Migraine focused on measuring Migraine, Common Migraine, Classic Migraine, Headache, Topiramate, Prophylaxis, Prevention
Eligibility Criteria
Inclusion Criteria: Medical history consistent with migraine with or without aura according to the International Headache Society (IHS) for at least 6 months prior to the study Between 3 to 12 migraine periods and no greater than 15 headache days (migraine and non-migraine) per month during the Baseline Phase No clinically significant abnormalities on neurological exams, electrocardiogram (ECG) or clinical laboratory test results at baseline Female patients must be postmenopausal for at least 1 year, surgically incapable of childbearing, practicing abstinence, or practicing an acceptable method of contraception (requires negative pregnancy test) Exclusion Criteria: Patients with headaches other than migraine Patients with episodic tension or sinus headaches Onset of migraine after age of 50 years Patients who have failed more than two adequate regimens for migraine prophylaxis Patients who overuse pain medications or certain other medications