The Study to Compare Cypher Versus Cypher Select in Treating Cornary Artery Lesions. (DOMINO)

Inclusion Criteria: Diagnosis of angina pectoris as defined by Canadian Cardiovascular Society Classification (CCS I, II, III, IV) OR unstable angina pectoris (Braunwald Classification B&C, I-II-III) OR patients with documented silent ischemia; Single treatment of de novo lesion in a coronary artery which can be appropriately covered by a study stent up to 23mm in length in patients with single or multivessel disease; patients with multiple lesions can be included only if the other lesions are successfully treated before the target lesion; Target lesion is more than 2.5 and less than 3.5mm in diameter (visual estimate); Target lesion is located in a native coronary artery with a maximum lesion length that can be adequately covered by a single 23 mm stent; Target lesion stenosis is > 50% and < 100% (visual estimate). Exclusion Criteria: A Q-wave or non-Q-wave myocardial infarction within the preceding 72 hours unless the CK and CK-MB enzymes are back to normal; Unprotected left main coronary disease with more than 50% stenosis; Significant (>50%) stenoses proximal or distal to the target lesion that might require revascularization or impede runoff; Have an ostial target lesion; Angiographic evidence of thrombus within target lesion; Calcified lesions which cannot be successfully predilated; Ejection fraction less than 30%; Totally occluded vessel (TIMI 0 level); Direct Stenting;