Study of Adherence Effects and Clinical Outcomes of Kaletra Based HIV Antiviral Therapy

Inclusion Criteria: Subject is documented HIV positive Subject is greater than or equal to 18 years of age. Subject currently on a regimen of either NNRTI + 2 Nucleoside Reverse Transcriptase Inhibitors NRTIs), two or three NRTIs who have failed regimen as evidenced by two consecutive viral loads with values over 1,000 copies/mL, the last one within the last three months, or Naïve subjects to ARV regimen who are required to begin a PI containing HAART regimen, or Subjects who have become intolerant to their current antiretroviral regimen and are required to be changed to a first time PI containing HAART regimen. Subject had laboratory testing within the previous three months and the most recent testing demonstrates all of the following: Hemoglobin >8.0 g/dL; Absolute neutrophil count >750 cells/mL; Platelet count >20,000/mL; ALT or AST <3 x Upper Limit of Normal (ULN); Creatinine <1.5 x ULN; Triglycerides <750 mg/dL. Subjects have no have evidence of grade III or IV adverse event or laboratory abnormality. Exclusion Criteria: -