Garlic in Patients With Febrile Neutropenia
Chemotherapy, Neutropenia
About this trial
This is an interventional prevention trial for Chemotherapy focused on measuring neutropenia, fever, garlic, infection
Eligibility Criteria
Inclusion Criteria: FN patients expected to have at least 5 days or more of neutropenia will be eligible for treatment with garlic compounds AST/ALT ≤ 3 times the upper limit of institutional laboratory normal. Total bilirubin ≤ 2 times the upper limit of institutional laboratory normal. BUN and creatinine should be ≤ 3 times the upper limit of institutional laboratory normal. Newly diagnosed as well as previously treated patients will be eligible. Exclusion Criteria: History of clinically significant liver or kidney disease. Patients on anti-coagulation therapy with Coumadin will be excluded because of the potential garlic interference with metabolism. Patients receiving concomitant chemotherapeutic treatment
Sites / Locations
- Hadassah Medical OrganizationRecruiting
Arms of the Study
Arm 1
Arm 2
Experimental
Placebo Comparator
Garlic extract
Placebo
Garlic extract capsules
Placebo capsules