A Study of Monthly Risedronate for Osteoporosis
Postmenopausal Osteoporosis
About this trial
This is an interventional treatment trial for Postmenopausal Osteoporosis focused on measuring randomized controlled trial, osteoporosis, risedronate
Eligibility Criteria
Inclusion Criteria: Female: 50 years of age or older >5 years since last menses natural or surgical have lumbar spine BMD (bone mineral density) more that 2.5 standard deviations (SD) below the young adult mean, or have 1-spine BMD more than 2.0 SD below the young adult female mean value and also have at least one prevalent vertebral body fracture Exclusion Criteria: history of uncontrolled hyperparathyroidism, hyperthyroidism, osteomalacia BMI (body mass index) >32 kg/m^2 use of medications within 3 months of starting study drug that impact bone metabolism such as glucocorticoids, estrogens, calcitonin, calcitriol, other bisphosphonates and parathyroid hormone hypocalcemia or hypercalcemia of any cause markedly abnormal clinical laboratory measurements that are assessed as clinically significant by the investigator
Sites / Locations
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Arms of the Study
Arm 1
Arm 2
Active Comparator
Experimental
1
2
5 mg risedronate, once daily for 2 years
150 mg risedronate taken once a month for 2 years