A Study of the Safety and Effectiveness of Levofloxacin Compared to Ticarcillin/Clavulanate Alone or Followed by Amoxicillin/Clavulanate in the Treatment of Complicated Skin Infections
Skin Diseases, Bacterial
About this trial
This is an interventional treatment trial for Skin Diseases, Bacterial focused on measuring skin infection, bacterial infection, levofloxacin, quinolones, skin, infection
Eligibility Criteria
Inclusion Criteria: Diagnosis of bacterial skin and skin structure infection with a complicating factor, (including a pre-existing skin lesion, or a condition affecting the way the drug gets to the infected area of the body, the body's disease defense (immune) system, or the ability of tissues to heal properly) have at least 2 of the following signs and symptoms of skin infection: pain, redness, swelling, hardness, pus formation have an infection of one of the following types: wound infections (crush, puncture, cut, gunshot, surgery, bite), infected skin ulcers, or infections in patients with decreased immune system function (HIV infections, diabetes, etc) able to provide a sample of tissue from the affected area of the skin Exclusion Criteria: Patients with multiple infected ulcers at separate locations on body requiring immediate surgery at the infection site having low blood pressure, decreased urination, decreased kidney function, seizure disorder, unstable mental disorder, low white blood cell count, bone infection, shock, or are HIV positive having an infection from a bacteria known to be resistant to any of the study drugs having a previous allergic or serious reaction to any of the study drugs