A Study of the Effectiveness and Safety of Risperidone Versus Placebo in the Treatment of Manic or Mixed Episodes Associated With Bipolar I Disorder
Bipolar Disorder, Manic Episode
About this trial
This is an interventional treatment trial for Bipolar Disorder focused on measuring risperidone, antipsychotic agents, bipolar disorders, manic episode
Eligibility Criteria
Inclusion Criteria: Meets DSM-IV criteria for Bipolar I Disorder, Most Recent Episode Manic or Mixed hospitalized voluntarily at study initiation for treatment of manic episode history (prior to study initiation) of at least one documented manic or mixed episode that required treatment total score >=20 on the Young Mania Rating Scale (YMRS) at start of the study Exclusion Criteria: Meets DSM-IV criteria for Schizoaffective Disorder or for rapid cycling borderline or antisocial personality disorder history of substance dependence (excluding nicotine and caffeine) within the 3 months prior to study initiation seizure disorder females who are pregnant or nursing, or those lacking adequate contraception.