Psychiatric Correlates of Psychogenic Movement Disorder and Non-Epileptic Seizure
Psychogenic Movement Disorders, Non-epileptic Seizures
About this trial
This is an observational trial for Psychogenic Movement Disorders focused on measuring Conversion Disorder, Somatoform Disorder, Involuntary Movement, Childhood Abuse, Depression, Psychogenic Movement Disorder, PMD, Non-Epileptic Seizure, NES, Healthy Volunteer, HV
Eligibility Criteria
INCLUSION CRITERIA: Patients for dissociation study: Diagnosis of clinically definite PMD utilizing Fahn and Williams criteria. The diagnosis will be made by a movement disorders neurologist. Or a diagnosis of NES based on video-EEG. The diagnosis will be made by an epileptologist. Males or females Age 18 or older Able to provide informed consent Patients for cognitive study: Diagnosis of clinically definite PMD utilizing Fahn and Williams criteria. The diagnosis will be made by a movement disorders neurologist. Age 18 or older Males or females Able to provide informed consent Normal volunteers for cognitive study: Normal volunteers age 18 or older will be included Males or females Able to provide informed consent EXCLUSION CRITERIA: Patients for dissociation study: Diagnosis of probable or possible PMD using Fahn and Williams criteria. Patients with neurological disorders with elaboration of their underlying disease process including comorbid epilepsy. Patients with a medical condition that prevents them from taking part in the study. Patients with current suicidal ideation. Patients with a psychotic disorder. Patients with active substance abuse within the last 6 months. Patients below the age of 18. Patients who are not capable of consent. Patients with an IQ less than 55. Patients currently involved in lawsuits. Patients for cognitive study: Diagnosis of probable or possible PMD using Fahn and Williams criteria Patients with neurological disorders with elaboration of their underlying disease process including comorbid epilepsy Patients with a medical condition that prevents them from taking part in the study. Patients with a history of a neurological disorder (e.g. dementia, cerebrovascular accident, neurodegenerative disorder, inflammatory disorders or infections of the central nervous system) that may result in cognitive deficits. Patients with a history of traumatic brain injury resulting in loss of consciousness or amnesia lasting for more than a few seconds. Patients with a psychotic disorder or bipolar disorder Patients with a current major depression Patients with current moderate to severe anxiety (Hamilton Anxiety Rating Scale greater than 25) Patients with current attention deficit hyperactivity disorder. Patients with active substance abuse within the last 6 months. Patient with current suicidal ideation. Patients below the age of 18. Patients who are not capable of consent. Patients with an IQ less than 55. Patients currently involved in lawsuits. Normal volunteers for cognitive study: Normal volunteers younger than 18 years Normal volunteers with an active medical condition that might prevent participation. Normal volunteers with a history of neurological disorders (e.g. dementia, cerebrovascular accident, neurodegenerative disorder, inflammatory disorders or infections of the central nervous system) that may result in cognitive deficits Normal volunteers with a history of traumatic brain injury resulting in loss of consciousness or amnesia lasting for more than a few seconds Normal volunteers with a psychotic disorder or bipolar disorder Normal volunteers with a current major depression Normal volunteers with moderate to severe anxiety (Hamilton Anxiety Rating Scale greater than 25) Normal volunteers with active substance abuse within the last 6 months Normal volunteers with current attention deficit hyperactivity disorder Normal volunteers with an IQ less than 55 Normal volunteers who are not capable of consent
Sites / Locations
- National Institutes of Health Clinical Center, 9000 Rockville Pike