Immune Response to Mycobacterium Tuberculosis Infection
Latent Tuberculosis
About this trial
This is an observational trial for Latent Tuberculosis focused on measuring Latent Tuberculosis, PPD, Antigen Specific T-Cells, Lymphocyte Proliferation Assay, HIV, LPA
Eligibility Criteria
INCLUSION CRITERIA: Age18 yrs. or older. Adequate venous access. Willingness to allow blood samples to be used for future studies of immune function and disease pathogenesis. Ability to give informed consent and willingness to comply with study requirements and procedures. Willingness to have PPD placed. Willingness to undergo HIV testing. EXCLUSION CRITERIA: Hgb less than or equal to 7.9 g/dl A known medical disorder or other circumstance which in the opinion of the PI might make the participation of the individual unsafe or difficult. Active TB or a history of treated tuberculosis infection. Presently suffering from an acute infection. History of a severe reaction to PPD application or known allergy to a component of the PPD. Severe burns or Eczema. PPD less than or equal to 8 weeks previously.
Sites / Locations
- National Institutes of Health Clinical Center, 9000 Rockville Pike
- Mali-NIAID HIV Research Initiative FMPOS