Arterial Closure vs Direct Compression for Hemostasis After PCI - The ACDC Trial
Coronary Angioplasty, Coronary Artery Disease
About this trial
This is an interventional treatment trial for Coronary Angioplasty focused on measuring Closure device, Stenting, Percutaneous coronary intervention
Eligibility Criteria
Inclusion Criteria: Patients undergoing elective PCI procedures. Femoral artery anatomy favorable for the placement of a closure device Planned use of clopidogrel and platelet glycoprotein IIb/IIIa antagonist Exclusion Criteria: Emergency PCI End stage renal disease Hemoglobin level < 100g/l Fish Allergy. Known allergy to Protamine. Use of low molecular weight heparin within last 12 hours. Prior closure device use within 90 days. Symptomatic peripheral vascular disease. Femoral artery calcification on fluoroscopy. Arterial puncture of the superficial femoral artery. Double wall puncture (puncture of anterior & posterior wall of femoral artery). Placement of intra aortic balloon pump. Placement of a femoral venous sheath. Coronary dissection, thrombus or perforation not resolved by the end of case
Sites / Locations
- St. Michael's Hospital
Arms of the Study
Arm 1
Arm 2
Active Comparator
Active Comparator
Direct Compression
Closure Device