Infrared Thermography in Finding Skin Lesions in Patients With Kaposi's Sarcoma
Primary Purpose
Sarcoma
Status
Terminated
Phase
Not Applicable
Locations
United States
Study Type
Interventional
Intervention
diagnostic imaging
Sponsored by
About this trial
This is an interventional diagnostic trial for Sarcoma focused on measuring Kaposi sarcoma
Eligibility Criteria
DISEASE CHARACTERISTICS: Meets 1 of the following criteria: Histologically confirmed cutaneous Kaposi's sarcoma (KS) At least one skin lesion accessible for imaging HIV positivity with proven cutaneous KS and concurrent visceral or mucous membrane involvement allowed Healthy volunteer (regardless of HIV status) (control) PATIENT CHARACTERISTICS: Performance status Not specified Life expectancy Not specified Hematopoietic Not specified Hepatic Not specified Renal Not specified Other Pregnancy allowed PRIOR CONCURRENT THERAPY: Prior topical, intralesional, or systemic treatment allowed
Sites / Locations
- Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
Outcomes
Primary Outcome Measures
Secondary Outcome Measures
Full Information
NCT ID
NCT00265902
First Posted
December 14, 2005
Last Updated
March 18, 2019
Sponsor
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
Collaborators
National Cancer Institute (NCI)
1. Study Identification
Unique Protocol Identification Number
NCT00265902
Brief Title
Infrared Thermography in Finding Skin Lesions in Patients With Kaposi's Sarcoma
Official Title
Ultra-Sensitive, Infra-Red Thermographic Analysis of Kaposi's Sarcoma Skin Lesions
Study Type
Interventional
2. Study Status
Record Verification Date
June 2006
Overall Recruitment Status
Terminated
Why Stopped
low accrual
Study Start Date
October 3, 2005 (Actual)
Primary Completion Date
March 21, 2006 (Actual)
Study Completion Date
March 21, 2006 (Actual)
3. Sponsor/Collaborators
Responsible Party, by Official Title
Sponsor
Name of the Sponsor
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
Collaborators
National Cancer Institute (NCI)
4. Oversight
5. Study Description
Brief Summary
RATIONALE: Diagnostic procedures, such as infrared thermography, may help find Kaposi's sarcoma and learn the extent of disease.
PURPOSE: This clinical trial is studying how well infrared thermography finds skin lesions in patients with Kaposi's sarcoma.
Detailed Description
OBJECTIVES:
Primary
Compare ultra-sensitive infrared thermographic images with visible light digital photographic images and clinical dermatologic examination as methods of measuring cutaneous lesions in patients with Kaposi's sarcoma (KS).
Secondary
Compare differences in modulation of temperature detected in KS skin lesions with non-involved skin of the same patient and with normal skin of healthy volunteers by sequential imaging using the infrared thermographic camera.
OUTLINE: This is a controlled, pilot study.
Patients undergo clinical assessment followed by simultaneous digital photographic camera imaging and high-resolution infrared thermographic camera imaging of designated normal skin areas and selected marker lesions. Before imaging, a metal bar chilled to 0º C, 10º C, and 25º C is applied to the lesions and designated normal skin areas for up to 90 seconds.
Healthy volunteers (controls) undergo the same procedure as for the patient except only designated normal skin areas are used.
PROJECTED ACCRUAL: A total of 20 patients and 10 healthy volunteers (controls) will be accrued for this study.
6. Conditions and Keywords
Primary Disease or Condition Being Studied in the Trial, or the Focus of the Study
Sarcoma
Keywords
Kaposi sarcoma
7. Study Design
Primary Purpose
Diagnostic
Study Phase
Not Applicable
Enrollment
3 (Actual)
8. Arms, Groups, and Interventions
Intervention Type
Procedure
Intervention Name(s)
diagnostic imaging
10. Eligibility
Sex
All
Minimum Age & Unit of Time
18 Years
Maximum Age & Unit of Time
120 Years
Accepts Healthy Volunteers
No
Eligibility Criteria
DISEASE CHARACTERISTICS:
Meets 1 of the following criteria:
Histologically confirmed cutaneous Kaposi's sarcoma (KS)
At least one skin lesion accessible for imaging
HIV positivity with proven cutaneous KS and concurrent visceral or mucous membrane involvement allowed
Healthy volunteer (regardless of HIV status) (control)
PATIENT CHARACTERISTICS:
Performance status
Not specified
Life expectancy
Not specified
Hematopoietic
Not specified
Hepatic
Not specified
Renal
Not specified
Other
Pregnancy allowed
PRIOR CONCURRENT THERAPY:
Prior topical, intralesional, or systemic treatment allowed
Overall Study Officials:
First Name & Middle Initial & Last Name & Degree
Ciro Martins, MD
Organizational Affiliation
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
Official's Role
Study Chair
Facility Information:
Facility Name
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
City
Baltimore
State/Province
Maryland
ZIP/Postal Code
21231-2410
Country
United States
12. IPD Sharing Statement
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Infrared Thermography in Finding Skin Lesions in Patients With Kaposi's Sarcoma
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