RCT Comparing Methadone and Buprenorphine in Pregnant Women
Opioid Related Disorders, Pregnancy, Opioid Dependence
About this trial
This is an interventional treatment trial for Opioid Related Disorders focused on measuring opiate addiction, opiate dependence, substance abuse, addiction, substance addiction, pregnancy, buprenorphine, methadone, fetal, neonatal, post-partum
Eligibility Criteria
Inclusion Criteria: Current opioid dependence Current opioid use, as determined by a urine drug test Pregnant with a single child with a gestational age of 6 to 30 weeks, as determined by a sonogram Exclusion Criteria: Current medical condition that would make study participation dangerous, as determined by study physician Diagnosed with an acute, severe psychiatric illness Current SCID I-E module diagnosis of benzodiazepine or alcohol abuse Use of alcohol or benzodiazepines in the 30 days prior to study entry, as determined by the Addiction Severity Index Pending legal action that may prohibit or interfere with study participation
Sites / Locations
- Johns Hopkins University School of Medicine
- Wayne State University
- Thomas Jefferson University
- Brown University
- Vanderbilt University
- University of Vermont
- Medical University of Vienna
- St. Joseph's Health Centre
Arms of the Study
Arm 1
Arm 2
Experimental
Active Comparator
Buprenorphine
Methadone
Buprenorphine
Methadone