Back to resultsDN-101 in Combination With Docetaxel in Androgen-Independent Prostate Cancer (AIPC) (AIPC Study of Calcitriol Enhancing Taxotere [ASCENT-2])
Primary Purpose
Prostate Cancer
Status
Terminated
Phase
Phase 3
Locations
International
Study Type
Interventional
Intervention
calcitriol
docetaxel
Sponsored by
About this trial
This is an interventional treatment trial for Prostate Cancer focused on measuring Androgen-independent Prostate Cancer (AIPC), Prostate Cancer, DN-101, calcitriol, Taxotere, docetaxel
Eligibility Criteria
Inclusion Criteria: Histopathologically or cytologically proven adenocarcinoma of the prostate Documented metastatic prostate adenocarcinoma Documented progression while on androgen ablation therapy detected by rising prostate specific antigen (PSA) and/or imaging Age >= 18 years Eastern Cooperative Oncology Group (ECOG) performance status <= 2 Adequate hematologic, renal and hepatic function Life expectancy >= 3 months Exclusion Criteria: Prior chemotherapy, except estramustine Prior chemotherapy with docetaxel Prior isotope therapy (e.g., strontium-89, samarium-153, etc.) One or more contraindications to the use of corticosteroids History of cancer-related hypercalcemia
Sites / Locations
- Birmingham Hematology & Oncology Associates, LLC
- Northwest Alabama Cancer Center
- Alaska Clinical Research Center
- Hematology Associates - AOA
- Premiere Oncology of Arizona
- Northern Arizona Hematology & Oncology Associates, AOA
- Southern Arizona VA Healthcare System
- U of Arizona / Arizona Cancer Center
- Genesis Cancer Center
- Tower Cancer Research Foundation
- Pacific Shores Medical Group
- The Angeles Clinic and Research Institute, Inc.
- UCLA department of Urology
- Veterans Affairs Northern California Health Care System
- Sutter Gould Medical Foundation
- Monterey Bay Oncology
- Comprehensive Cancer Center at
- Sutter Cancer Center
- UCD Cancer Center-Clinical Trials
- Sharp Memorial Hospital
- California Pacific Medical Center
- Stanford University
- Rocky Mountain Cancer Centers
- Georgetown University Lombardi Cancer Center
- Pasco Hernando Oncology Associates, P.A.
- North Broward Medical Center
- Florida Cancer Specialists
- Broward Oncology Associates
- Michael and Dianne Bienes Comprehensive Cancer Center
- Gainesville Hematology Oncology Associates
- University of Florida Shands Cancer Center
- Integrated Community Oncology Network
- Sylvester Comprehensive Cancer Center, U of Miami
- Innovative Medical Research of South Florida Inc.
- Pasco Hernando Oncology Associates P.A.
- Florida Cancer Institute
- Ocala Oncology Center
- Cancer Centers of Florida, P.A.
- AYS Urology
- Phoebe Cancer Center
- Northeast Georgia Cancer Care, LLC
- Peachtree Hematology-Oncology Consultants, PC
- Atlanta Cancer Care
- Northeast GA Medical Center
- Georgia Cancer Specialist
- South Georgia Medical Center
- Hematology Oncology Associates of Illinois
- Midwest Prostate & Urology Health Center
- Cancer Care & Hematology Specialists of Chicagoland
- Oncology Specialists
- Swedish American Regional Cancer Center
- Hematology Oncology Associates of Illinois, L.L.C
- Central Indiana Cancer Centers
- Medical Consultants, PC c/o Ball Cancer Center
- Northern Indiana Cancer Research Consortium
- Hope Center
- Medical Center of Vincennes
- Iowa Cancer Care
- Mercy Medical Center, North Iowa
- Siouxland Hematology-Oncology Associates
- University of Kansas Medical Center
- Hematology Oncology Life Center
- Maine Center for Cancer Medicine & Blood Disorders
- St. Agnes Health System
- Maryland Oncology Hematology, P.A.
- Frederick Memorial Hospital
- Henry Ford Health System
- Minnesota Oncology Hematology, P.A.
- MN Cooperative Group Outreach Prg.
- Park Nicollet Institute
- Park Nicollet Institute
- Missouri Cancer Associates
- University of Missouri, Ellis Fischel Cancer Center
- St. Joseph Oncology, Inc.
- Nebraska Hematology-Oncology, PC
- Nebraska Methodist Hospital - Oncology Research Dept
- Horizon's West Medical Group
- Comprehensive Cancer Centers of Nevada
- Nevada Cancer Institute
- UMDNJ-Newark
- The Valley Hospital
- Overlook Oncology Center
- New Mexico Cancer Care Associates
- SUNY Downstate Medical Center
- Hematology Oncology Associates of
- Memorial Sloan-Kett
- Interlakes Foundation Inc.
- University of Rochester Medical Center
- Staten Island Urological Research, PC
- Raleigh Hematology Oncology Associates
- Carolina Cancer Management, Inc.
- Piedmont Hematology Oncology Associates, PLLC
- Dakota Cancer Institute
- Aultman Hospital
- Gabrail Cancer Center
- Oncology Hematology Care, Inc.
- The Cleveland Clinic Foundation
- Mid Ohio Oncology/Hematology, Inc.
- Dayton Oncology & Hematology, P.A.
- University of Oklahoma
- Cancer Care Associates
- Cancer Care Associates
- Willamette Valley Cancer Center
- Consultants in Medical Oncology & Hematology
- Hematology & Oncology Associates of Northeastern PA
- Medical Oncology Associates of Wyoming Valley, PC
- St. Mary Medical Center
- Greater Philadelphia Cancer
- Univeristy of Pittsburgh Cancer Institute
- Pottsville Cancer Care
- Guthrie Clinic
- Charleston Hematology Oncology PA
- Charleston Cancer Center
- Medical University Of South Carolina
- Cancer Centers of the Carolina
- South Carolina Cancer Specialists
- Chattanooga Oncology & Hematology Assoc.
- The Jones Clinic
- Sarah Cannon Research Institute
- Texas Cancer Center-Abilene
- Texas Oncology, PA
- Texas Cancer Center
- Urology Associates of North Texas (UANT)
- Texas Oncology Cancer Center
- MamieMcFaddin Ward Cancer Center
- Texas Cancer Center ar Medical City
- Center for Oncology Research and Treatment, PA
- Texas Oncology, P.A.
- The Texas Cancer Center
- El Paso Cancer Treatment Center-East
- Texas Oncology, P.A.
- The Center for Cancer & Blood Disorders
- Texas Oncology, P.A.
- Texas Oncology, P.A.
- Lake Vista Cancer Center
- Texas Oncology, P.A.
- Southwest Cancer Treatment and Research Center
- South Texas Cancer Center - McAllen
- Texas Cancer Center of Mesquite
- Allison Cancer Center
- Cancer Care Network of South Texas, HOAST
- West Texas Cancer Center
- Paris Regional Cancer Center
- South Texas Oncology and Hematology, PA
- InVisions Consultants LLC
- Texas Cancer Center- Sherman
- Texas Oncology Cancer Center-Sugar Land
- Texas Oncology
- Texas Oncology Cancer Care and Research Center
- Fairfax Northern Virginia Hematology OnCology, PC
- Virginia Oncology Associates
- Oncology & Hematology Associates of Southwest Virginia, Inc.
- Highline Medical Oncology
- Puget Sound Cancer Centers
- University of Washington
- Puget Sound Cancer Centers
- Northwest Cancer Specialists, P.C.
- Wenatchee Valley Medical Center
- Yakima Valley Memorial Hospital/North Star Lodge
- Medical College of Wisconsin
- Tom Baker Cancer Center-Medical Oncology
- Cross Cancer Institute
- BCCA-Centre for the Southern Interior
- BCCA-Vancouver
- British Columbia Cancer Agency - Vancouver Island Centre
- Cancer Care Manitoba
- The Moncton Hospital (SERHA)
- Dr. Leon Richard Oncology Center
- Centre for Clinical Research Cancer Care Program
- Jaravinski Cancer Centre Hamilton Health Services
- Cancer Centre of Southeastern Ontario
- London Regional Cancer Program
- The Ottawa Hospital Regional Cancer Centre
- Regional Cancer Program de l'Hopital Regional de Sudbury
- Toronto Sunnybrook Regional Cancer Centre
- Windsor Regional Cancer Centre
- McGill University
- Saskatoon Cancer Centre
- Institute of Radiation Oncology of Teaching Hospital Na Bulovce
- Department of Radiation and Oncology of Teaching Hospital Motol
- Teaching Hospital Kralovske Vinohrady
- Clinical Center Niš - Clinic of Urology
- Universitätsklinikum Köln
- Gemeinschaftspraxis für Hämatologie & Onkologie
- Facharzt f. Urologie
- Urologische Praxis
- Universitatsmedizin Charité
- Klinik am Urban
- Universitätsmedizin Charité Campus Benjamin Franklin
- Urologische Praxis
- Städtisches Klinikum Braunschweig
- Facharzt f. Urologie
- Urologische Klinik
- Universitäsklinikum Düsseldorf
- Urologische Klinik der Universitätsklink Düsseldorf
- Universitätsklinikum Essen
- Klinikum Fulda, Urologische Klinik
- Urologische Praxis
- Urologische Gemeinschaftspraxis
- Medizinische Hochschule Hannover
- Nationales Centrum für Tumorerkrankungen
- Universitätsklinikum Homburg/Saar
- Klinikum Kassel GmbH
- Gemeinschaftspraxis für Urologie
- Gesellschaft f. klinische Studien und Urologisches Gesundheitszentrum
- Oberarzt d. Urolog. Abteilung
- Obearzt der Urologischen Klinik, Universitätsklinik Münster
- Praxisgemeinschaft für Onkologie und Urologie
- Gemeinschaftspraxis f. Urologie
- Urologische Praxis
- IRM Center Hospital and Institutes, II.Department of Oncology
- Uzsoki Hospital of the Local Authority of Budapest, Oncoradiology
- University of Debrecen, Medical and Health Science Center, Department of Oncology
- University of Szeged, Szent-Györgyi Albert Medical and Pharmacist Science Center, Clinic of Oncotherapy
- San Juan VA Medical Center, Reseach Dept
- Cabinetul de Urologie
- Policlinica de diagnostic rapid
- Institutul Oncologic Bucuresti
- Euro S.R.L.
- ProVita 2000
- Theaching Hospital of F.D. Roosevelt
- Faculty Hospital Martin
- Faculty Hospital of J. A. Reiman
Outcomes
Primary Outcome Measures
Secondary Outcome Measures
Full Information
1. Study Identification
Unique Protocol Identification Number
NCT00273338
Brief Title
DN-101 in Combination With Docetaxel in Androgen-Independent Prostate Cancer (AIPC) (AIPC Study of Calcitriol Enhancing Taxotere [ASCENT-2])
Official Title
A Phase 3, Randomized, Open-Label Study Evaluating DN-101 in Combination With Docetaxel in Androgen-Independent Prostate Cancer (AIPC) (ASCENT-2)
Study Type
Interventional
2. Study Status
Record Verification Date
November 2007
Overall Recruitment Status
Terminated
Why Stopped
DSMB
Study Start Date
January 2006 (undefined)
Primary Completion Date
undefined (undefined)
Study Completion Date
November 2007 (Actual)
3. Sponsor/Collaborators
Name of the Sponsor
Novacea
4. Oversight
5. Study Description
Brief Summary
The primary objective of this study is:
To evaluate the effect of DN-101 in combination with docetaxel (ASCENT regimen) on survival in metastatic androgen-independent prostate cancer
The secondary objectives of this study are:
To determine the effect of the ASCENT regimen on the rate of thromboembolic events (blood clots)
To determine the effect of the ASCENT regimen on prevention of skeletal-related events (fractures)
A Separate sub-study will be conducted at selected study sites in North America to determine the population PK of DN-101.
6. Conditions and Keywords
Primary Disease or Condition Being Studied in the Trial, or the Focus of the Study
Prostate Cancer
Keywords
Androgen-independent Prostate Cancer (AIPC), Prostate Cancer, DN-101, calcitriol, Taxotere, docetaxel
7. Study Design
Primary Purpose
Treatment
Study Phase
Phase 3
Interventional Study Model
Parallel Assignment
Masking
None (Open Label)
Allocation
Randomized
Enrollment
1200 (Anticipated)
8. Arms, Groups, and Interventions
Intervention Type
Drug
Intervention Name(s)
calcitriol
Intervention Type
Drug
Intervention Name(s)
docetaxel
10. Eligibility
Sex
Male
Minimum Age & Unit of Time
18 Years
Accepts Healthy Volunteers
No
Eligibility Criteria
Inclusion Criteria:
Histopathologically or cytologically proven adenocarcinoma of the prostate
Documented metastatic prostate adenocarcinoma
Documented progression while on androgen ablation therapy detected by rising prostate specific antigen (PSA) and/or imaging
Age >= 18 years
Eastern Cooperative Oncology Group (ECOG) performance status <= 2
Adequate hematologic, renal and hepatic function
Life expectancy >= 3 months
Exclusion Criteria:
Prior chemotherapy, except estramustine
Prior chemotherapy with docetaxel
Prior isotope therapy (e.g., strontium-89, samarium-153, etc.)
One or more contraindications to the use of corticosteroids
History of cancer-related hypercalcemia
Overall Study Officials:
First Name & Middle Initial & Last Name & Degree
Howard I. Scher, MD
Organizational Affiliation
Sidney Kimmel Center for Prostate and Urologic Cancers, Memorial Sloan Kettering Cancer Center
Official's Role
Study Chair
First Name & Middle Initial & Last Name & Degree
Kim N. Chi, M.D.
Organizational Affiliation
British Columbia Cancer Agency - Vancouver Centre
Official's Role
Study Chair
First Name & Middle Initial & Last Name & Degree
Ronald De-Wit, M.D.
Organizational Affiliation
Erasmus University Medical Center (Netherlands)
Official's Role
Study Chair
Facility Information:
Facility Name
Birmingham Hematology & Oncology Associates, LLC
City
Birmingham
State/Province
Alabama
ZIP/Postal Code
35223
Country
United States
Facility Name
Northwest Alabama Cancer Center
City
Muscle Shoals
State/Province
Alabama
ZIP/Postal Code
35661
Country
United States
Facility Name
Alaska Clinical Research Center
City
Anchorage
State/Province
Alaska
ZIP/Postal Code
99508
Country
United States
Facility Name
Hematology Associates - AOA
City
Phoenix
State/Province
Arizona
ZIP/Postal Code
85012
Country
United States
Facility Name
Premiere Oncology of Arizona
City
Scottsdale
State/Province
Arizona
ZIP/Postal Code
85260
Country
United States
Facility Name
Northern Arizona Hematology & Oncology Associates, AOA
City
Sedona
State/Province
Arizona
ZIP/Postal Code
86336
Country
United States
Facility Name
Southern Arizona VA Healthcare System
City
Tucson
State/Province
Arizona
ZIP/Postal Code
85723
Country
United States
Facility Name
U of Arizona / Arizona Cancer Center
City
Tucson
State/Province
Arizona
ZIP/Postal Code
85724
Country
United States
Facility Name
Genesis Cancer Center
City
Hot Springs
State/Province
Arkansas
ZIP/Postal Code
71913
Country
United States
Facility Name
Tower Cancer Research Foundation
City
Beverly Hills
State/Province
California
ZIP/Postal Code
90211-1850
Country
United States
Facility Name
Pacific Shores Medical Group
City
Long Beach
State/Province
California
ZIP/Postal Code
90813
Country
United States
Facility Name
The Angeles Clinic and Research Institute, Inc.
City
Los Angeles
State/Province
California
ZIP/Postal Code
90025
Country
United States
Facility Name
UCLA department of Urology
City
Los Angeles
State/Province
California
ZIP/Postal Code
90095-1738
Country
United States
Facility Name
Veterans Affairs Northern California Health Care System
City
Martinez
State/Province
California
ZIP/Postal Code
94553
Country
United States
Facility Name
Sutter Gould Medical Foundation
City
Modesto
State/Province
California
ZIP/Postal Code
95355
Country
United States
Facility Name
Monterey Bay Oncology
City
Monterey
State/Province
California
ZIP/Postal Code
93940
Country
United States
Facility Name
Comprehensive Cancer Center at
City
Palm Springs
State/Province
California
ZIP/Postal Code
92262
Country
United States
Facility Name
Sutter Cancer Center
City
Sacramento
State/Province
California
ZIP/Postal Code
95816
Country
United States
Facility Name
UCD Cancer Center-Clinical Trials
City
Sacramento
State/Province
California
ZIP/Postal Code
95817
Country
United States
Facility Name
Sharp Memorial Hospital
City
San Diego
State/Province
California
ZIP/Postal Code
92123
Country
United States
Facility Name
California Pacific Medical Center
City
San Francisco
State/Province
California
ZIP/Postal Code
94115
Country
United States
Facility Name
Stanford University
City
Stanford
State/Province
California
ZIP/Postal Code
94305
Country
United States
Facility Name
Rocky Mountain Cancer Centers
City
Colorado Springs
State/Province
Colorado
ZIP/Postal Code
80909
Country
United States
Facility Name
Georgetown University Lombardi Cancer Center
City
Washington
State/Province
District of Columbia
ZIP/Postal Code
20007
Country
United States
Facility Name
Pasco Hernando Oncology Associates, P.A.
City
14529 Cortez Blvd.
State/Province
Florida
ZIP/Postal Code
34613
Country
United States
Facility Name
North Broward Medical Center
City
Deerfield Beach
State/Province
Florida
ZIP/Postal Code
33064
Country
United States
Facility Name
Florida Cancer Specialists
City
Fort Myers
State/Province
Florida
ZIP/Postal Code
33901
Country
United States
Facility Name
Broward Oncology Associates
City
Ft. Lauderdale
State/Province
Florida
ZIP/Postal Code
33308
Country
United States
Facility Name
Michael and Dianne Bienes Comprehensive Cancer Center
City
Ft. Lauderdale
State/Province
Florida
ZIP/Postal Code
33308
Country
United States
Facility Name
Gainesville Hematology Oncology Associates
City
Gainesville
State/Province
Florida
ZIP/Postal Code
32605
Country
United States
Facility Name
University of Florida Shands Cancer Center
City
Gainesville
State/Province
Florida
ZIP/Postal Code
32611
Country
United States
Facility Name
Integrated Community Oncology Network
City
Jacksonville
State/Province
Florida
ZIP/Postal Code
32256
Country
United States
Facility Name
Sylvester Comprehensive Cancer Center, U of Miami
City
Miami
State/Province
Florida
ZIP/Postal Code
33136
Country
United States
Facility Name
Innovative Medical Research of South Florida Inc.
City
N. Miami Beach
State/Province
Florida
ZIP/Postal Code
33179
Country
United States
Facility Name
Pasco Hernando Oncology Associates P.A.
City
New Port Richey
State/Province
Florida
ZIP/Postal Code
34652
Country
United States
Facility Name
Florida Cancer Institute
City
New Port Richey
State/Province
Florida
ZIP/Postal Code
34655
Country
United States
Facility Name
Ocala Oncology Center
City
Ocala
State/Province
Florida
ZIP/Postal Code
34474
Country
United States
Facility Name
Cancer Centers of Florida, P.A.
City
Ocoee
State/Province
Florida
ZIP/Postal Code
34761
Country
United States
Facility Name
AYS Urology
City
Trinity
State/Province
Florida
ZIP/Postal Code
34655
Country
United States
Facility Name
Phoebe Cancer Center
City
Albany
State/Province
Georgia
ZIP/Postal Code
31701
Country
United States
Facility Name
Northeast Georgia Cancer Care, LLC
City
Athens
State/Province
Georgia
ZIP/Postal Code
30607
Country
United States
Facility Name
Peachtree Hematology-Oncology Consultants, PC
City
Atlanta
State/Province
Georgia
ZIP/Postal Code
30309
Country
United States
Facility Name
Atlanta Cancer Care
City
Atlanta
State/Province
Georgia
ZIP/Postal Code
30342
Country
United States
Facility Name
Northeast GA Medical Center
City
Gainesville
State/Province
Georgia
ZIP/Postal Code
30501
Country
United States
Facility Name
Georgia Cancer Specialist
City
Tucker
State/Province
Georgia
ZIP/Postal Code
30084
Country
United States
Facility Name
South Georgia Medical Center
City
Valdosta
State/Province
Georgia
ZIP/Postal Code
31602
Country
United States
Facility Name
Hematology Oncology Associates of Illinois
City
Chicago
State/Province
Illinois
ZIP/Postal Code
60611
Country
United States
Facility Name
Midwest Prostate & Urology Health Center
City
Chicago
State/Province
Illinois
ZIP/Postal Code
60640
Country
United States
Facility Name
Cancer Care & Hematology Specialists of Chicagoland
City
Niles
State/Province
Illinois
ZIP/Postal Code
60714
Country
United States
Facility Name
Oncology Specialists
City
Park Ridge
State/Province
Illinois
ZIP/Postal Code
60068
Country
United States
Facility Name
Swedish American Regional Cancer Center
City
Rockford
State/Province
Illinois
ZIP/Postal Code
61104
Country
United States
Facility Name
Hematology Oncology Associates of Illinois, L.L.C
City
Skokie
State/Province
Illinois
ZIP/Postal Code
60077
Country
United States
Facility Name
Central Indiana Cancer Centers
City
Indianapolis
State/Province
Indiana
ZIP/Postal Code
46227
Country
United States
Facility Name
Medical Consultants, PC c/o Ball Cancer Center
City
Muncie
State/Province
Indiana
ZIP/Postal Code
47303
Country
United States
Facility Name
Northern Indiana Cancer Research Consortium
City
South Bend
State/Province
Indiana
ZIP/Postal Code
46601
Country
United States
Facility Name
Hope Center
City
Terre Haute
State/Province
Indiana
ZIP/Postal Code
47802
Country
United States
Facility Name
Medical Center of Vincennes
City
Vincennes
State/Province
Indiana
ZIP/Postal Code
47591
Country
United States
Facility Name
Iowa Cancer Care
City
Cedar Rapids
State/Province
Iowa
ZIP/Postal Code
52403
Country
United States
Facility Name
Mercy Medical Center, North Iowa
City
Mason City
State/Province
Iowa
ZIP/Postal Code
50401
Country
United States
Facility Name
Siouxland Hematology-Oncology Associates
City
Sioux City
State/Province
Iowa
ZIP/Postal Code
51101
Country
United States
Facility Name
University of Kansas Medical Center
City
Kansas City
State/Province
Kansas
ZIP/Postal Code
66160
Country
United States
Facility Name
Hematology Oncology Life Center
City
Alexandria
State/Province
Louisiana
ZIP/Postal Code
71301
Country
United States
Facility Name
Maine Center for Cancer Medicine & Blood Disorders
City
Scarborough
State/Province
Maine
ZIP/Postal Code
04074
Country
United States
Facility Name
St. Agnes Health System
City
Baltimore
State/Province
Maryland
ZIP/Postal Code
21229
Country
United States
Facility Name
Maryland Oncology Hematology, P.A.
City
Columbia
State/Province
Maryland
ZIP/Postal Code
21044
Country
United States
Facility Name
Frederick Memorial Hospital
City
Frederick
State/Province
Maryland
ZIP/Postal Code
21701
Country
United States
Facility Name
Henry Ford Health System
City
Detroit
State/Province
Michigan
ZIP/Postal Code
48202
Country
United States
Facility Name
Minnesota Oncology Hematology, P.A.
City
Minneapolis
State/Province
Minnesota
ZIP/Postal Code
55404
Country
United States
Facility Name
MN Cooperative Group Outreach Prg.
City
Minneapolis
State/Province
Minnesota
ZIP/Postal Code
55407
Country
United States
Facility Name
Park Nicollet Institute
City
Saint Louis Park
State/Province
Minnesota
ZIP/Postal Code
55416
Country
United States
Facility Name
Park Nicollet Institute
City
St. Louis Park
State/Province
Minnesota
ZIP/Postal Code
55416
Country
United States
Facility Name
Missouri Cancer Associates
City
Columbia
State/Province
Missouri
ZIP/Postal Code
65201
Country
United States
Facility Name
University of Missouri, Ellis Fischel Cancer Center
City
Columbia
State/Province
Missouri
ZIP/Postal Code
65203
Country
United States
Facility Name
St. Joseph Oncology, Inc.
City
St. Joseph
State/Province
Missouri
ZIP/Postal Code
64507
Country
United States
Facility Name
Nebraska Hematology-Oncology, PC
City
Lincoln
State/Province
Nebraska
ZIP/Postal Code
68506
Country
United States
Facility Name
Nebraska Methodist Hospital - Oncology Research Dept
City
Omaha
State/Province
Nebraska
ZIP/Postal Code
68144
Country
United States
Facility Name
Horizon's West Medical Group
City
Scottsbluff
State/Province
Nebraska
ZIP/Postal Code
69361
Country
United States
Facility Name
Comprehensive Cancer Centers of Nevada
City
Las Vegas
State/Province
Nevada
ZIP/Postal Code
89109
Country
United States
Facility Name
Nevada Cancer Institute
City
Las Vegas
State/Province
Nevada
ZIP/Postal Code
89135
Country
United States
Facility Name
UMDNJ-Newark
City
Newark
State/Province
New Jersey
ZIP/Postal Code
07101
Country
United States
Facility Name
The Valley Hospital
City
Paramus
State/Province
New Jersey
ZIP/Postal Code
07652
Country
United States
Facility Name
Overlook Oncology Center
City
Summit
State/Province
New Jersey
ZIP/Postal Code
07901
Country
United States
Facility Name
New Mexico Cancer Care Associates
City
Sante Fe
State/Province
New Mexico
ZIP/Postal Code
87505
Country
United States
Facility Name
SUNY Downstate Medical Center
City
Brooklyn
State/Province
New York
ZIP/Postal Code
11203
Country
United States
Facility Name
Hematology Oncology Associates of
City
New City
State/Province
New York
ZIP/Postal Code
10956
Country
United States
Facility Name
Memorial Sloan-Kett
City
New York
State/Province
New York
ZIP/Postal Code
10021
Country
United States
Facility Name
Interlakes Foundation Inc.
City
Rochester
State/Province
New York
ZIP/Postal Code
14623
Country
United States
Facility Name
University of Rochester Medical Center
City
Rochester
State/Province
New York
ZIP/Postal Code
14642
Country
United States
Facility Name
Staten Island Urological Research, PC
City
Staten Island
State/Province
New York
ZIP/Postal Code
10304
Country
United States
Facility Name
Raleigh Hematology Oncology Associates
City
Cary
State/Province
North Carolina
ZIP/Postal Code
27511
Country
United States
Facility Name
Carolina Cancer Management, Inc.
City
Fayetteville
State/Province
North Carolina
ZIP/Postal Code
28304
Country
United States
Facility Name
Piedmont Hematology Oncology Associates, PLLC
City
Winston-Salem
State/Province
North Carolina
ZIP/Postal Code
27103
Country
United States
Facility Name
Dakota Cancer Institute
City
Fargo
State/Province
North Dakota
ZIP/Postal Code
58103
Country
United States
Facility Name
Aultman Hospital
City
Canton
State/Province
Ohio
ZIP/Postal Code
44710
Country
United States
Facility Name
Gabrail Cancer Center
City
Canton
State/Province
Ohio
ZIP/Postal Code
44718
Country
United States
Facility Name
Oncology Hematology Care, Inc.
City
Cincinnati
State/Province
Ohio
ZIP/Postal Code
45242
Country
United States
Facility Name
The Cleveland Clinic Foundation
City
Cleveland
State/Province
Ohio
ZIP/Postal Code
44195
Country
United States
Facility Name
Mid Ohio Oncology/Hematology, Inc.
City
Columbus
State/Province
Ohio
ZIP/Postal Code
43213
Country
United States
Facility Name
Dayton Oncology & Hematology, P.A.
City
Kettering
State/Province
Ohio
ZIP/Postal Code
45409
Country
United States
Facility Name
University of Oklahoma
City
Oklahoma City
State/Province
Oklahoma
ZIP/Postal Code
73104
Country
United States
Facility Name
Cancer Care Associates
City
Oklahoma City
State/Province
Oklahoma
ZIP/Postal Code
73112
Country
United States
Facility Name
Cancer Care Associates
City
Tulsa
State/Province
Oklahoma
ZIP/Postal Code
74136
Country
United States
Facility Name
Willamette Valley Cancer Center
City
Eugene
State/Province
Oregon
ZIP/Postal Code
97401-8122
Country
United States
Facility Name
Consultants in Medical Oncology & Hematology
City
Drexel Hill
State/Province
Pennsylvania
ZIP/Postal Code
19026
Country
United States
Facility Name
Hematology & Oncology Associates of Northeastern PA
City
Dunmore
State/Province
Pennsylvania
ZIP/Postal Code
18512
Country
United States
Facility Name
Medical Oncology Associates of Wyoming Valley, PC
City
Kingston
State/Province
Pennsylvania
ZIP/Postal Code
18704
Country
United States
Facility Name
St. Mary Medical Center
City
Langhorne
State/Province
Pennsylvania
ZIP/Postal Code
19047
Country
United States
Facility Name
Greater Philadelphia Cancer
City
Philadelphia
State/Province
Pennsylvania
ZIP/Postal Code
19114
Country
United States
Facility Name
Univeristy of Pittsburgh Cancer Institute
City
Pittsburgh
State/Province
Pennsylvania
ZIP/Postal Code
15232
Country
United States
Facility Name
Pottsville Cancer Care
City
Pottsville
State/Province
Pennsylvania
ZIP/Postal Code
17901
Country
United States
Facility Name
Guthrie Clinic
City
Sayre
State/Province
Pennsylvania
ZIP/Postal Code
18840
Country
United States
Facility Name
Charleston Hematology Oncology PA
City
Charleston
State/Province
South Carolina
ZIP/Postal Code
29403
Country
United States
Facility Name
Charleston Cancer Center
City
Charleston
State/Province
South Carolina
ZIP/Postal Code
29406
Country
United States
Facility Name
Medical University Of South Carolina
City
Charleston
State/Province
South Carolina
ZIP/Postal Code
29425
Country
United States
Facility Name
Cancer Centers of the Carolina
City
Greenville
State/Province
South Carolina
ZIP/Postal Code
29615
Country
United States
Facility Name
South Carolina Cancer Specialists
City
Hilton Head Island
State/Province
South Carolina
ZIP/Postal Code
29926
Country
United States
Facility Name
Chattanooga Oncology & Hematology Assoc.
City
Chattanooga
State/Province
Tennessee
ZIP/Postal Code
TN
Country
United States
Facility Name
The Jones Clinic
City
Germantown
State/Province
Tennessee
ZIP/Postal Code
38138
Country
United States
Facility Name
Sarah Cannon Research Institute
City
Nashville
State/Province
Tennessee
ZIP/Postal Code
37203
Country
United States
Facility Name
Texas Cancer Center-Abilene
City
Abilene
State/Province
Texas
ZIP/Postal Code
79606-5208
Country
United States
Facility Name
Texas Oncology, PA
City
Amarillo
State/Province
Texas
ZIP/Postal Code
79106
Country
United States
Facility Name
Texas Cancer Center
City
Arlington
State/Province
Texas
ZIP/Postal Code
76014
Country
United States
Facility Name
Urology Associates of North Texas (UANT)
City
Arlington
State/Province
Texas
ZIP/Postal Code
76017
Country
United States
Facility Name
Texas Oncology Cancer Center
City
Austin
State/Province
Texas
ZIP/Postal Code
78731
Country
United States
Facility Name
MamieMcFaddin Ward Cancer Center
City
Beaumont
State/Province
Texas
ZIP/Postal Code
77702-1449
Country
United States
Facility Name
Texas Cancer Center ar Medical City
City
Dallas
State/Province
Texas
ZIP/Postal Code
75230-2510
Country
United States
Facility Name
Center for Oncology Research and Treatment, PA
City
Dallas
State/Province
Texas
ZIP/Postal Code
75230
Country
United States
Facility Name
Texas Oncology, P.A.
City
Dallas
State/Province
Texas
ZIP/Postal Code
75231-4400
Country
United States
Facility Name
The Texas Cancer Center
City
Dallas
State/Province
Texas
ZIP/Postal Code
75237
Country
United States
Facility Name
El Paso Cancer Treatment Center-East
City
El Paso
State/Province
Texas
ZIP/Postal Code
79915
Country
United States
Facility Name
Texas Oncology, P.A.
City
Fort Worth
State/Province
Texas
ZIP/Postal Code
76104
Country
United States
Facility Name
The Center for Cancer & Blood Disorders
City
Fort Worth
State/Province
Texas
ZIP/Postal Code
76104
Country
United States
Facility Name
Texas Oncology, P.A.
City
Garland
State/Province
Texas
ZIP/Postal Code
75042-5788
Country
United States
Facility Name
Texas Oncology, P.A.
City
Houston
State/Province
Texas
ZIP/Postal Code
77024
Country
United States
Facility Name
Lake Vista Cancer Center
City
Lewisville
State/Province
Texas
ZIP/Postal Code
75067
Country
United States
Facility Name
Texas Oncology, P.A.
City
Longview
State/Province
Texas
ZIP/Postal Code
75601
Country
United States
Facility Name
Southwest Cancer Treatment and Research Center
City
Lubbock
State/Province
Texas
ZIP/Postal Code
79415
Country
United States
Facility Name
South Texas Cancer Center - McAllen
City
McAllen
State/Province
Texas
ZIP/Postal Code
78503
Country
United States
Facility Name
Texas Cancer Center of Mesquite
City
Mesquite
State/Province
Texas
ZIP/Postal Code
75150
Country
United States
Facility Name
Allison Cancer Center
City
Midland
State/Province
Texas
ZIP/Postal Code
79701-5946
Country
United States
Facility Name
Cancer Care Network of South Texas, HOAST
City
New Braunfels
State/Province
Texas
ZIP/Postal Code
78131
Country
United States
Facility Name
West Texas Cancer Center
City
Odessa
State/Province
Texas
ZIP/Postal Code
79761
Country
United States
Facility Name
Paris Regional Cancer Center
City
Paris
State/Province
Texas
ZIP/Postal Code
75460-5004
Country
United States
Facility Name
South Texas Oncology and Hematology, PA
City
San Antonio
State/Province
Texas
ZIP/Postal Code
78229
Country
United States
Facility Name
InVisions Consultants LLC
City
San Antonio
State/Province
Texas
ZIP/Postal Code
78233
Country
United States
Facility Name
Texas Cancer Center- Sherman
City
Sherman
State/Province
Texas
ZIP/Postal Code
75090-0504
Country
United States
Facility Name
Texas Oncology Cancer Center-Sugar Land
City
Sugar Land
State/Province
Texas
ZIP/Postal Code
77479
Country
United States
Facility Name
Texas Oncology
City
Waco
State/Province
Texas
ZIP/Postal Code
76022
Country
United States
Facility Name
Texas Oncology Cancer Care and Research Center
City
Waco
State/Province
Texas
ZIP/Postal Code
76712
Country
United States
Facility Name
Fairfax Northern Virginia Hematology OnCology, PC
City
Fairfax
State/Province
Virginia
ZIP/Postal Code
22031
Country
United States
Facility Name
Virginia Oncology Associates
City
Norfolk
State/Province
Virginia
ZIP/Postal Code
23502
Country
United States
Facility Name
Oncology & Hematology Associates of Southwest Virginia, Inc.
City
Salem
State/Province
Virginia
ZIP/Postal Code
24153
Country
United States
Facility Name
Highline Medical Oncology
City
Burien
State/Province
Washington
ZIP/Postal Code
98166
Country
United States
Facility Name
Puget Sound Cancer Centers
City
Edmonds
State/Province
Washington
ZIP/Postal Code
98026
Country
United States
Facility Name
University of Washington
City
Seattle
State/Province
Washington
ZIP/Postal Code
98109
Country
United States
Facility Name
Puget Sound Cancer Centers
City
Seattle
State/Province
Washington
ZIP/Postal Code
98133
Country
United States
Facility Name
Northwest Cancer Specialists, P.C.
City
Vancouver
State/Province
Washington
ZIP/Postal Code
98684
Country
United States
Facility Name
Wenatchee Valley Medical Center
City
Wenatchee
State/Province
Washington
ZIP/Postal Code
98801
Country
United States
Facility Name
Yakima Valley Memorial Hospital/North Star Lodge
City
Yakima
State/Province
Washington
ZIP/Postal Code
98902
Country
United States
Facility Name
Medical College of Wisconsin
City
Milwaukee
State/Province
Wisconsin
ZIP/Postal Code
53226
Country
United States
Facility Name
Tom Baker Cancer Center-Medical Oncology
City
Calgary
State/Province
Alberta
ZIP/Postal Code
T2N4N2
Country
Canada
Facility Name
Cross Cancer Institute
City
Edmonton
State/Province
Alberta
ZIP/Postal Code
T6G 1Z2
Country
Canada
Facility Name
BCCA-Centre for the Southern Interior
City
Kelowna
State/Province
British Columbia
ZIP/Postal Code
V1Y 5L3
Country
Canada
Facility Name
BCCA-Vancouver
City
Vancouver
State/Province
British Columbia
ZIP/Postal Code
V5Z4E6
Country
Canada
Facility Name
British Columbia Cancer Agency - Vancouver Island Centre
City
Victoria
State/Province
British Columbia
ZIP/Postal Code
V8R 6V5
Country
Canada
Facility Name
Cancer Care Manitoba
City
Winnipeg
State/Province
Manitoba
ZIP/Postal Code
R3E0V9
Country
Canada
Facility Name
The Moncton Hospital (SERHA)
City
Moncton
State/Province
New Brunswick
ZIP/Postal Code
E1C 6Z8
Country
Canada
Facility Name
Dr. Leon Richard Oncology Center
City
Moncton
State/Province
New Brunswick
ZIP/Postal Code
EIC8X3
Country
Canada
Facility Name
Centre for Clinical Research Cancer Care Program
City
Halifax
State/Province
Nova Scotia
ZIP/Postal Code
B3H 1V7
Country
Canada
Facility Name
Jaravinski Cancer Centre Hamilton Health Services
City
Hamilton
State/Province
Ontario
ZIP/Postal Code
L8V 5C2
Country
Canada
Facility Name
Cancer Centre of Southeastern Ontario
City
Kingston
State/Province
Ontario
ZIP/Postal Code
K7L 5P9
Country
Canada
Facility Name
London Regional Cancer Program
City
London
State/Province
Ontario
ZIP/Postal Code
N6A 4L6
Country
Canada
Facility Name
The Ottawa Hospital Regional Cancer Centre
City
Ottawa
State/Province
Ontario
ZIP/Postal Code
K1H 8L6
Country
Canada
Facility Name
Regional Cancer Program de l'Hopital Regional de Sudbury
City
Sudbury
State/Province
Ontario
ZIP/Postal Code
P3E 5J1
Country
Canada
Facility Name
Toronto Sunnybrook Regional Cancer Centre
City
Toronto
State/Province
Ontario
ZIP/Postal Code
M4N 3M5
Country
Canada
Facility Name
Windsor Regional Cancer Centre
City
Windsor
State/Province
Ontario
ZIP/Postal Code
N8W 2X3
Country
Canada
Facility Name
McGill University
City
Montreal
State/Province
Quebec
ZIP/Postal Code
H2W 1S6
Country
Canada
Facility Name
Saskatoon Cancer Centre
City
Saskatoon
State/Province
Saskatchewan
ZIP/Postal Code
S7N 4H4
Country
Canada
Facility Name
Institute of Radiation Oncology of Teaching Hospital Na Bulovce
City
Prague
ZIP/Postal Code
180 81
Country
Czech Republic
Facility Name
Department of Radiation and Oncology of Teaching Hospital Motol
City
Prague
Country
Czech Republic
Facility Name
Teaching Hospital Kralovske Vinohrady
City
Prague
Country
Czech Republic
Facility Name
Clinical Center Niš - Clinic of Urology
City
Belgrade
ZIP/Postal Code
18000
Country
Former Serbia and Montenegro
Facility Name
Universitätsklinikum Köln
City
Köln
State/Province
50931
Country
Germany
Facility Name
Gemeinschaftspraxis für Hämatologie & Onkologie
City
Augsburg
ZIP/Postal Code
86150
Country
Germany
Facility Name
Facharzt f. Urologie
City
Bad Schwartau
ZIP/Postal Code
23611
Country
Germany
Facility Name
Urologische Praxis
City
Bautzen
ZIP/Postal Code
02625
Country
Germany
Facility Name
Universitatsmedizin Charité
City
Berlin
ZIP/Postal Code
10117
Country
Germany
Facility Name
Klinik am Urban
City
Berlin
ZIP/Postal Code
10967
Country
Germany
Facility Name
Universitätsmedizin Charité Campus Benjamin Franklin
City
Berlin
ZIP/Postal Code
12200
Country
Germany
Facility Name
Urologische Praxis
City
Berlin
Country
Germany
Facility Name
Städtisches Klinikum Braunschweig
City
Braunschweig
ZIP/Postal Code
38126
Country
Germany
Facility Name
Facharzt f. Urologie
City
Cottbus
ZIP/Postal Code
03046
Country
Germany
Facility Name
Urologische Klinik
City
Dresden
ZIP/Postal Code
01307
Country
Germany
Facility Name
Universitäsklinikum Düsseldorf
City
Düsseldorf
ZIP/Postal Code
40225
Country
Germany
Facility Name
Urologische Klinik der Universitätsklink Düsseldorf
City
Düsseldorf
ZIP/Postal Code
40225
Country
Germany
Facility Name
Universitätsklinikum Essen
City
Essen
Country
Germany
Facility Name
Klinikum Fulda, Urologische Klinik
City
Fulda
ZIP/Postal Code
36043
Country
Germany
Facility Name
Urologische Praxis
City
Hagenow
Country
Germany
Facility Name
Urologische Gemeinschaftspraxis
City
Hamburg
ZIP/Postal Code
22399
Country
Germany
Facility Name
Medizinische Hochschule Hannover
City
Hannover
ZIP/Postal Code
30625
Country
Germany
Facility Name
Nationales Centrum für Tumorerkrankungen
City
Heidelberg
ZIP/Postal Code
69120
Country
Germany
Facility Name
Universitätsklinikum Homburg/Saar
City
Homburg
Country
Germany
Facility Name
Klinikum Kassel GmbH
City
Kassel
ZIP/Postal Code
34125
Country
Germany
Facility Name
Gemeinschaftspraxis für Urologie
City
Kirchheim/Teck
ZIP/Postal Code
73230
Country
Germany
Facility Name
Gesellschaft f. klinische Studien und Urologisches Gesundheitszentrum
City
Leipzig
Country
Germany
Facility Name
Oberarzt d. Urolog. Abteilung
City
München
ZIP/Postal Code
81675
Country
Germany
Facility Name
Obearzt der Urologischen Klinik, Universitätsklinik Münster
City
Münster
ZIP/Postal Code
48149
Country
Germany
Facility Name
Praxisgemeinschaft für Onkologie und Urologie
City
Wilhelmshaven
ZIP/Postal Code
26389
Country
Germany
Facility Name
Gemeinschaftspraxis f. Urologie
City
Wuppertal
ZIP/Postal Code
42103
Country
Germany
Facility Name
Urologische Praxis
City
Zwickau
Country
Germany
Facility Name
IRM Center Hospital and Institutes, II.Department of Oncology
City
Budapest
ZIP/Postal Code
1071
Country
Hungary
Facility Name
Uzsoki Hospital of the Local Authority of Budapest, Oncoradiology
City
Budapest
ZIP/Postal Code
H-1145
Country
Hungary
Facility Name
University of Debrecen, Medical and Health Science Center, Department of Oncology
City
Debrecen
ZIP/Postal Code
H4032
Country
Hungary
Facility Name
University of Szeged, Szent-Györgyi Albert Medical and Pharmacist Science Center, Clinic of Oncotherapy
City
Szeged
Country
Hungary
Facility Name
San Juan VA Medical Center, Reseach Dept
City
San Juan
ZIP/Postal Code
00921
Country
Puerto Rico
Facility Name
Cabinetul de Urologie
City
Arad
ZIP/Postal Code
310175
Country
Romania
Facility Name
Policlinica de diagnostic rapid
City
Brasov
ZIP/Postal Code
500366
Country
Romania
Facility Name
Institutul Oncologic Bucuresti
City
Bucuresti
Country
Romania
Facility Name
Euro S.R.L.
City
Cluj Napoca
ZIP/Postal Code
400046
Country
Romania
Facility Name
ProVita 2000
City
Constanta
ZIP/Postal Code
900635
Country
Romania
Facility Name
Theaching Hospital of F.D. Roosevelt
City
Banska Bystrica
ZIP/Postal Code
97517
Country
Slovakia
Facility Name
Faculty Hospital Martin
City
Martin
ZIP/Postal Code
03659
Country
Slovakia
Facility Name
Faculty Hospital of J. A. Reiman
City
Presov
Country
Slovakia
12. IPD Sharing Statement
Learn more about this trial
DN-101 in Combination With Docetaxel in Androgen-Independent Prostate Cancer (AIPC) (AIPC Study of Calcitriol Enhancing Taxotere [ASCENT-2])
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