Controlled Trial of Valacyclovir in Infectious Mononucleosis
Infectious Mononucleosis
About this trial
This is an interventional treatment trial for Infectious Mononucleosis focused on measuring infectious mononucleosis, Epstein-Barr virus, valacyclovir, quantitative PCR
Eligibility Criteria
Inclusion Criteria: Clinical diagnosis of infectious mononucleosis with onset no more the 7 days before enrollment; willingness to sign informed consent Willingness to provide blood and oral washing samples at regular intervals Females must have a negative urine pregnancy test and agree to use effective contraception (barrier or hormonal) for the first 30 days of the study if assigned to valacyclovir Corticosteroids are permitted only if prescribed by the subject's primary physisican for treatment of this acute disease Exclusion Criteria: Previous history of mono Pregnant or breast feeding End-stage renal or liver disease Immunosuppressed due to underlying medical disease and/or immunomodulating medications prior to enrollment Onset of present illness >7 days ago
Sites / Locations
- University of Minnesota Clinical Virology Clinic