Back to resultsImprovement in Baroreflex Sensitivity in OSAS
Primary Purpose
Obstructive Sleep Apnea Syndrome
Status
Unknown status
Phase
Not Applicable
Locations
Japan
Study Type
Interventional
Intervention
continuous positive airway pressure therapy
Sponsored by
About this trial
This is an interventional treatment trial for Obstructive Sleep Apnea Syndrome focused on measuring obstructive sleep apnea,, baroreceptors
Eligibility Criteria
Inclusion Criteria: obstructive sleep apnea syndrome Exclusion Criteria: diabetes mellitus, chronic obstructive lung disease, coronary or valvular heart disease, congestive heart failure, renal failure, or endocrine dysfunction. Moreover, none of them were taking b-blockers, vasodilators, or inotropic agents at the time of enrollment in the study.
Sites / Locations
- Nagoya University of Health SciencesRecruiting
Outcomes
Primary Outcome Measures
Secondary Outcome Measures
Full Information
1. Study Identification
Unique Protocol Identification Number
NCT00284037
Brief Title
Improvement in Baroreflex Sensitivity in OSAS
Study Type
Interventional
2. Study Status
Record Verification Date
May 2005
Overall Recruitment Status
Unknown status
Study Start Date
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Primary Completion Date
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Study Completion Date
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3. Sponsor/Collaborators
Name of the Sponsor
Nagoya University
4. Oversight
5. Study Description
Brief Summary
Individuals with obstructive sleep apnea syndrome (OSAS) are at high risk for cardiovascular morbidity and mortality. The effect of long-term nocturnal therapy with continuous positive airway pressure (CPAP) on daytime baroreflex sensitivity (BRS), a predictor of cardiac death, was investigated in OSAS patients.
6. Conditions and Keywords
Primary Disease or Condition Being Studied in the Trial, or the Focus of the Study
Obstructive Sleep Apnea Syndrome
Keywords
obstructive sleep apnea,, baroreceptors
7. Study Design
Primary Purpose
Treatment
Study Phase
Not Applicable
Interventional Study Model
Parallel Assignment
Masking
None (Open Label)
Allocation
Randomized
8. Arms, Groups, and Interventions
Intervention Type
Device
Intervention Name(s)
continuous positive airway pressure therapy
10. Eligibility
Sex
All
Minimum Age & Unit of Time
20 Years
Maximum Age & Unit of Time
70 Years
Eligibility Criteria
Inclusion Criteria:
obstructive sleep apnea syndrome
Exclusion Criteria:
diabetes mellitus, chronic obstructive lung disease, coronary or valvular heart disease, congestive heart failure, renal failure, or endocrine dysfunction. Moreover, none of them were taking b-blockers, vasodilators, or inotropic agents at the time of enrollment in the study.
Central Contact Person:
First Name & Middle Initial & Last Name or Official Title & Degree
Akiko Noda, PhD
Phone
+81-52-719-1537
Email
a-noda@met.nagoya-u.ac.jp
Overall Study Officials:
First Name & Middle Initial & Last Name & Degree
Mitsuhiro Yokota, MD.PhD
Organizational Affiliation
Department of Cardiovascular Genome Science, Nagoya University School of Medicine, Nagoya, Aichi, Japan
Official's Role
Study Chair
Facility Information:
Facility Name
Nagoya University of Health Sciences
City
Nagoya
ZIP/Postal Code
461-8673
Country
Japan
Individual Site Status
Recruiting
Facility Contact:
First Name & Middle Initial & Last Name & Degree
Akiko Noda, PhD
Phone
+81-719-1537
Email
a-noda@met.nagoya-u.ac.jp
First Name & Middle Initial & Last Name & Degree
Akiko Noda, PhD
12. IPD Sharing Statement
Learn more about this trial
Improvement in Baroreflex Sensitivity in OSAS
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