Cholesterol-Lowering Effects of Policosanol
Hypercholesterolemia, Combined Hyperlipidemia
About this trial
This is an interventional treatment trial for Hypercholesterolemia
Eligibility Criteria
Inclusion Criteria: Isolated hypercholesterolaemia or combined hyperlipidaemia with mean LDL values at Visits 2 and 3 of > 150 mg/dl for patients with no or one risk factor (other than known coronary artery disease) or 150-189 mg/dl for patients with two or more risk factors for the development of cardiovascular events (males > 45 years of age, females > 55 years of age or postmenopausal), known coronary artery disease, uncontrolled hypertension > 140 mm Hg systolic, HDL level < 35 mg/dl (mean of the values of visits 2 and 3), current cigarette smoking of > 10 cigarettes/day, obesity with BMI > 30 kg/m², family history of coronary heart disease), male or female patients aged from 18 to 80 years, negative pregnancy test for woman of childbearing potential, no communication problems with the investigator, availability of a signed informed consent to participate in the trial, for medical data to be recorded and made available to a third party. Exclusion Criteria: - known hypersensitivity to any component of the drug, myocardial infarction less than one year before clinical trial inclusion, PTCA or CABG less than one year before clinical trial inclusion, unstable angina pectoris, hypothyroidism, diabetes mellitus, acute inflammatory diseases, severe gastrointestinal diseases, triglycerides values > 500 mg/dl at Visit 2 or 3, use of oral systemic corticosteroids, anticoagulants or other lipid-lowering drugs, serious diseases or circumstances not allowing the patient's participation in the trial (e.g. malignoma, alcoholism or drug abuse, severe kidney and liver diseases), pregnancy, lactation and women of childbearing potential without employing a safe contraception method, participation in a clinical trial within the last 30 days before Visit 1, repeated inclusion in the present clinical trial.