Study of Scaling and Root Planing With PerioWave Versus Scaling and Root Planing Alone in Chronic Periodontitis
Periodontitis
About this trial
This is an interventional treatment trial for Periodontitis focused on measuring Chronic Periodontitis, Periodontitis, Photodynamic disinfection, PDD, PDT, Periowave, Scaling and Root Planing, SRP
Eligibility Criteria
Inclusion Criteria: Adult male or female over the age of 18 Having been diagnosed with chronic periodontitis >18 fully erupted teeth Has had no periodontal instrumentation in the four months prior to initiation of study treatment Subject has at least 4 sites with pocket depth of 6-9 mm in at least two quadrants of the mouth. Subject is willing and able to return for treatment and evaluation procedures scheduled throughout the course of this clinical study The subject is capable of giving informed consent Subject is willing to sign a consent form Exclusion Criteria: Is pregnant or nursing or who plans to become pregnant in the next 4 months Having significant liver disease by subject report Having an active malignancy of any type by subject report Having chronic disease or diminished mental capacity that would mitigate the ability to comply with the protocol Having any significant disease (either acute or chronic) or who is taking medication with concomitant oral manifestations that in the opinion of the investigator would interfere with evaluation of safety or efficacy of PerioWave® Having an active periapical abscess or periodontal abscess or a history of acute necrotizing ulcerative gingivitis Treatment with antibiotics within the 1-month period prior to beginning the study or any systemic condition which requires antibiotic coverage for routine periodontal procedures (e.g. heart conditions, joint replacements, etc) by report of the subject Known allergy to methylene blue Has glucose-6-phosphate dehydrogenase (G6PD) deficiency by subject report Currently uses anti-coagulant therapy at therapeutic doses Currently uses photosensitizing medications Participated in investigational treatment in the last 30 days or expectation for using a separate investigational treatment during the time of the study
Sites / Locations
- University of Alberta
- University of Western Ontario
- North York Dental Center
- University of Saskatchewan