search
Back to results

Changes in Brain Activity (Functional MRI Study) Before and After Behavioral Therapy of Height Phobia

Primary Purpose

Height Phobia, Fear of Heights

Status
Completed
Phase
Not Applicable
Locations
Study Type
Interventional
Intervention
Behavior therapy
Sponsored by
New York State Psychiatric Institute
About
Eligibility
Locations
Outcomes
Full info

About this trial

This is an interventional treatment trial for Height Phobia focused on measuring Height phobia, fear of heights, specific phobia

Eligibility Criteria

18 Years - 40 Years (Adult)All SexesAccepts Healthy Volunteers

Inclusion Criteria: Specific phobia of Heights Exclusion Criteria: History of medical problems

Sites / Locations

    Outcomes

    Primary Outcome Measures

    CGI

    Secondary Outcome Measures

    acrophobia questionnaire

    Full Information

    First Posted
    March 14, 2006
    Last Updated
    December 14, 2011
    Sponsor
    New York State Psychiatric Institute
    search

    1. Study Identification

    Unique Protocol Identification Number
    NCT00302978
    Brief Title
    Changes in Brain Activity (Functional MRI Study) Before and After Behavioral Therapy of Height Phobia
    Official Title
    The Effects of in Vivo Exposure Therapy on the Neural Correlates of Height Phobia: a Functional Magnetic Resonance Imaging Study Using a Fear Provocation Paradigm.
    Study Type
    Interventional

    2. Study Status

    Record Verification Date
    April 2007
    Overall Recruitment Status
    Completed
    Study Start Date
    March 2006 (undefined)
    Primary Completion Date
    undefined (undefined)
    Study Completion Date
    June 2006 (Actual)

    3. Sponsor/Collaborators

    Responsible Party, by Official Title
    Sponsor
    Name of the Sponsor
    New York State Psychiatric Institute

    4. Oversight

    5. Study Description

    Brief Summary
    We are interested in investigating the functional brain abnormalities of height phobia. Subjects will be have a functional MRI scan before and after a course of treatment with behavioral therapy.
    Detailed Description
    The purpose of this study is to investigate the effects of in vivo exposure therapy on the functional brain activity of subjects with height phobia using a fear provocation paradigm. We expect differential activation of the fear circuitry in height phobics compared to non-phobic controls, and that successful behavioral therapy will normalize the heightened fear response in height phobia.

    6. Conditions and Keywords

    Primary Disease or Condition Being Studied in the Trial, or the Focus of the Study
    Height Phobia, Fear of Heights
    Keywords
    Height phobia, fear of heights, specific phobia

    7. Study Design

    Primary Purpose
    Treatment
    Study Phase
    Not Applicable
    Interventional Study Model
    Parallel Assignment
    Masking
    None (Open Label)
    Allocation
    Non-Randomized
    Enrollment
    40 (false)

    8. Arms, Groups, and Interventions

    Intervention Type
    Behavioral
    Intervention Name(s)
    Behavior therapy
    Primary Outcome Measure Information:
    Title
    CGI
    Secondary Outcome Measure Information:
    Title
    acrophobia questionnaire

    10. Eligibility

    Sex
    All
    Minimum Age & Unit of Time
    18 Years
    Maximum Age & Unit of Time
    40 Years
    Accepts Healthy Volunteers
    Accepts Healthy Volunteers
    Eligibility Criteria
    Inclusion Criteria: Specific phobia of Heights Exclusion Criteria: History of medical problems
    Overall Study Officials:
    First Name & Middle Initial & Last Name & Degree
    Yujuan Choy, M.D.
    Organizational Affiliation
    New York State Psychiatric Institute, Columbia University
    Official's Role
    Principal Investigator

    12. IPD Sharing Statement

    Learn more about this trial

    Changes in Brain Activity (Functional MRI Study) Before and After Behavioral Therapy of Height Phobia

    We'll reach out to this number within 24 hrs