Effect of Quetiapine on Negative Symptoms and Cognition
Schizophrenia

About this trial
This is an interventional treatment trial for Schizophrenia
Eligibility Criteria
Inclusion Criteria: Signed informed consent men and women aged 18 to 65 years with diagnosis of schizophrenia score of at least 4 CGI, PANSS negative subscale score > 21 fulfil the criterion to be right-handed for inclusion in the fMRI investigations Exclusion Criteria: Substance or alcohol dependence female patients who are pregnant, lactating or at risk of pregnancy history of organic CNS-trauma, epilepsy, meningoencephalitis, psychosurgery, instable somatic conditions risk of suicide or aggressive behaviour history of electroconvulsive therapy, Parkinson's disease, Prolactin-dependent tumor For the subset of subjects for the fMRI investigations the following additional exclusion criteria is valid as: existence of metal in the body as by cardiac pacemaker, coil, total prosthesis, metal splinter, metal articulation, metal balls.
Sites / Locations
- Research Site