Study to Compare the Efficacy and Safety of Pitavastatin and Simvastatin
Hypercholesterolemia, Dyslipidemia
About this trial
This is an interventional treatment trial for Hypercholesterolemia focused on measuring hypercholesterolemia, kowa, dyslipidemia, pitavastatin, NK-104, Primary Hypercholesterolemia or Combined Dyslipidemia
Eligibility Criteria
Inclusion Criteria: Males and females (18-75 years) Must have been following a restrictive diet Diagnosis of primary hypercholesterolemia or combined dyslipidemia Exclusion Criteria: Homozygous familial hypercholesterolemia or familial hypoalphalipoproteinemia; Conditions which may cause secondary dyslipidemia. Uncontrolled diabetes mellitus (by hemoglobin A1c [HbA1c] > 8%) Abnormal serum creatine kinase (CK) above the pre-specified level Abnormal pancreatic, liver or renal function Significant heart disease
Sites / Locations
- Geri-Med Oy
- Kaisaniemen Laakariasema
- Keravan Laakarikeskus
- SOK-tyoterveyshuolto
- TYKS University Hospital
- Dipartimento Di Medicina Clinica e Biotecnologia Applicata
- Centro di Ricerca Clinica
- Gerontologia e Geriatria - Universita degli Studi
- Dipartimento di Medicina Interna DIMI
- Universita di Modena e Reggio Emilia, Policlinico
- Dipartimento di Medicina Clinica e Sperimentale
- Medicina Clinica e delle Patologie Emergenti
- Dipartimento di Medicina Interna e Scienze Biomediche
- U.O Malattie Metaboliche e Diabetologia
- Azienda Ospedaliero-Universitaria
- Volvat Medisinske Senter
- Nyomen Legekontor
- Radhuset Spesialistsenter
- Rikshospitalet - University Hospital
- Skedsmo Medisinske Senter A.S.
- Kemerovo Cardiology Dispensary
- Central Clinical Hospital 1 of RZD
- City Clinical Hospital 23
- City Clinical Hospital 64
- Moscow City Clinical Hospital 68
- State Research Center for Preventive Medicine
- Novosibirsk Reg. Clinical Cardiology Dispensary
- Central Medical Unit 122, St. Pb
- Clinical Hospital of Russian Academy of Sciences
- Consulting and Diagnostic Center 85
- Krestovsky Island Medical Institute
- Pokrovskaya City Hospital
- St Michael's Partnership
- Avondale Surgery
- Knowle House Surgery
- The Burngreave Surgery
- St Helier Hospital
- Box Surgery
- Eastleigh Surgery
- Lovemead Group Practice
- St Chad's Surgery
- The Health Centre
Arms of the Study
Arm 1
Arm 2
Arm 3
Arm 4
Experimental
Active Comparator
Experimental
Active Comparator
Pitavastatin 2 mg
Simvastatin 20 mg
Pitavastatin 4 mg
Simvastatin 40 mg
Pitavastatin 2 mg once daily
Simvastatin 20 mg once daily
Pitavastatin 4 mg once daily
Simvastatn 40 mg once daily