Trial Comparing BST-CarGel and Microfracture in Repair of Articular Cartilage Lesions in the Knee
Knee Injuries
About this trial
This is an interventional treatment trial for Knee Injuries focused on measuring Cartilage repair, Cartilage, Knee, Knee Pain, Microfracture, arthroscopy, bone marrow stimulation, Chondrogenesis, Scaffold, Chitosan, A02.165.165, A10.165.382.332, G07.574.500.325.377.625.180, A10.165.382.400, Articular Cartilage Repair
Eligibility Criteria
Inclusion Criteria: Between 18 and 55 years of age Focal articular cartilage lesion on the medial femoral condyle Grade 3 or 4 acute (traumatic) or chronic (degenerative) lesion Stable knee Exclusion Criteria: Multiple lesions or kissing lesions Clinically relevant compartment malalignment (> 5 degrees) Undergone ligament treatments in the affected knee within 2 years prior to trial Inflammatory arthropathy, such as rheumatoid arthritis, systemic lupus, or active gout Previous surgical cartilage treatments in the affected knee in the last 12 months
Sites / Locations
- Sports Medicine Centre - University of Calgary
- New West Sports Medicine
- Hospital at UBC
- Pan Am Clinic
- Orthopaedic and Sport Medicine Clinic of Nova Scotia
- Entralogix Clinical Group Inc.
- Sports Medicine Clinic - Carleton University
- Sunnybrook Health Sciences Centre, Div. of Orthopaedic Surgery
- Hopital Charles LeMoyne
- Hospital Sacré-Coeur de Montréal
- Centre Hospitalier Affilie Universitaire de Quebec et Hôpital Valcartier
- Seoul National University Hospital
- Kyung Hee University Medical Center
- Hospital Begona de Gijon
- FREMAP Centro de Prevención y Rehabilitación
- Hospital Clinic i Provincial de Barcelona
- Hospital Universitario Gregorio Maraňón
- Hospital La Paz
Arms of the Study
Arm 1
Arm 2
Experimental
Active Comparator
Microfracture with BST-CarGel
Microfracture without BST-CarGel
BST-CarGel applied to a Microfractured lesion in repair of focal articular cartilage lesions on the femoral condyle
Microfractured lesion in repair of focal articular cartilage lesions on the femoral condyle