A Trial of Pentoxifylline for the Treatment of Recurrent Aphthous Stomatitis
Recurrent Aphthous Stomatitis
About this trial
This is an interventional treatment trial for Recurrent Aphthous Stomatitis focused on measuring recurrent aphthous stomatitis, recurrent mouth ulcers, pentoxifylline, clinical trial, double blind, placebo controlled, randomized
Eligibility Criteria
Inclusion Criteria: Diagnosis of minor recurrent aphthous stomatitis 2 or more mouth ulcers per month for more than 6 No current treatment for oral ulceration or willing to stop treatment Age 16 to 65 years Exclusion Criteria: Taking ketorolac, theophylline or anti-hypertensive medication except diuretics (contra-indicated in patients treated with pentoxifylline) Systemic diseases that contra-indicate the use of pentoxifylline i.e. pregnancy, hypotension, ischaemic heart disease, acute myocardial infarction, cerebral or occular hemorrhage, renal or hepatic failure, porphyria or allergy to pentoxifylline. Patients with an underlying deficiency state or systemic disease that could cause recurrent mouth ulcers e.g. iron, vitamin B12 or foliate deficience, coeliac disease, Crohn's disease, ulcerative colitis, Behcet's disease or Aids.
Sites / Locations
- University Dental Hospital of Manchester