Gabapentin for the Treatment of Tinnitus
Tinnitus
About this trial
This is an interventional treatment trial for Tinnitus
Eligibility Criteria
Inclusion Criteria: Adults, between the ages of 18 and 70 Idiopathic, subjective, troublesome, unilateral or bilateral, non-pulsatile tinnitus (ICD-9 --388.31) of 6 month's duration or greater Tinnitus handicap score of 38 or greater on the Tinnitus Handicap Inventory. Exclusion Criteria: The symptoms of tinnitus can be affected by the concomitant use of tricyclic antidepressants, carbamazepine, phenytoin, valproate sodium, or benzodiazepines. Patients who have used these drugs within 30 days of screening will not be enrolled. Impaired renal function as determined from serum creatinine levels, using the following formulas35: adult male Ccr = (140 -age) X weight in kilograms/(72 X serum creatinine in milligrams per deciliter); and adult female Ccr = [(140 - age) X weight in kilograms/(72 X serum creatinine in milligrams per deciliter)] X 0.85,whereCcr indicates creatinine clearance. Patients with tinnitus related to cochlear implantation, retrocochlear lesion, or other known anatomic/structural lesions of the ear and temporal bone Patients with any serious or unstable medical or psychiatric condition. Patients whose ability to give informed consent is in question.