Epsilon-Aminocaproaic Acid to Reduce the Need for Blood Transfusions During and Following Spine Surgery
Scoliosis, Kyphosis, Lordosis
About this trial
This is an interventional treatment trial for Scoliosis focused on measuring Aminocaproic Acids, Blood Transfusion
Eligibility Criteria
Inclusion Criteria: Diagnosis of spondylosis, pseudoarthrosis, kyphoscoliosis, or acquired or congenital spine deformity Willing to undergo elective spinal surgery by a participating surgeon; eligible procedures include the following: spine osteotomy, arthrodesis, instrumentation and/or corpectomy, surgery for lumbar spinal stenosis, or surgery for degenerative disc disease Exclusion Criteria: Requires urgent or emergent surgery Has kidney failure that requires dialysis Has a known bleeding diathesis, defined as a documented history of an inherited bleeding disorder (e.g., hemophilia or von Willebrand's disease) OR prothrombin time ratio greater than 1.5 seconds OR a documented previous arterial or venous thrombosis within 1 year of study entry Pregnant
Sites / Locations
- Johns Hopkins Hospital
Arms of the Study
Arm 1
Arm 2
Experimental
Placebo Comparator
1
2
Participants will receive either EACA.
Participants will receive placebo.