Coronary Artery Revascularization in Diabetes (VA CARDS)

Inclusion Criteria: Patients with diabetes with severe coronary artery disease General Inclusion Criteria Age at least 18 years old Patients with either Type I or Type II diabetes with a documented HbA1c greater than site ULN (If not on diabetic medication must be confirmed by a blood glucose of >126 mg/dL fasting, or >200mg/dL non-fasting); OR on diabetic medication with a documented physician diagnosis of diabetes mellitus. No child bearing potential (if female) Patient competent to provide consent Exclusion Criteria: General Exclusion Criteria Congenital heart disease Coronary bypass surgery within the preceding one year Need for concomitant cardiac surgery AHA Class III decompensated heart failure or AHA Class IV heart failure Undergoing PCI for hemodynamic instability related to acute STEMI History of a hemorrhagic stroke Severe bleeding diathesis History of chronic pancreatitis A severe co-morbid condition that is expected to limit life to less than two years Embolic stroke in the past six months Significant GI bleed within the last one month Lack of adequate surgical conduit Sensitivity to clopidogrel (Plavix) Sensitivity to glycoprotein IIb/IIIa inhibitors Chronic systemic steroid use Participation in another trial with active intervention Patient unable to be adequately followed