Risperidone and Olanzapine for the Schizophrenic Patients With Neuroleptic-Induced Acute Dystonia or Parkinsonism
Schizophrenia, Extrapyramidal Syndrome
About this trial
This is an interventional treatment trial for Schizophrenia focused on measuring Schizophrenia, EPS, risperidone, olanzapine
Eligibility Criteria
Inclusion Criteria: Age of 18-65 y/o; Female patients did not have pregnancy plans and must agree to use reliable pregnancy prevention methods if during childbearing age; Meet schizophrenia criteria of DSM-IV; Fulfill DSM-IV neuroleptic-induced acute dystonia or parkinsonism research criteria, the severity of acute dystonia or parkinsonism was greater than moderate degree (>4) assessed by global impression of Extrapyramidal System Rating Scale (item 43 and 44 of ESRS); Patients or legal responsible people agree to join study and sign informed consent Exclusion Criteria: Had other axis I diagnosis of DSM-IV; Unstable major systemic diseases; Had neurological disorder influenced to EPS assessment; Substance abuse or dependence other then coffee or tobacco within 6 months before study
Sites / Locations
- Taoyuan Mental Hospital