Cognitive Remediation in Early Substance Abuse Treatment
Primary Purpose
Substance-Related Disorders
Status
Terminated
Phase
Not Applicable
Locations
United States
Study Type
Interventional
Intervention
Cognitive Remediation
Sponsored by
About this trial
This is an interventional treatment trial for Substance-Related Disorders focused on measuring Psychology: cognitive aspects, Substance-Related Disorders, treatment efficacy
Eligibility Criteria
Inclusion Criteria: Veterans participating in a substance abuse day treatment program at the Errara Community Center Exclusion Criteria:
Sites / Locations
- VA Connecticut Health Care System (West Haven)
Arms of the Study
Arm 1
Arm 2
Arm Type
Experimental
No Intervention
Arm Label
1
2
Arm Description
PSS CogRehab exercises
On-line computer games
Outcomes
Primary Outcome Measures
Cognitive improvement and adherence to substance abuse treatment
Secondary Outcome Measures
Full Information
NCT ID
NCT00334217
First Posted
June 2, 2006
Last Updated
June 17, 2009
Sponsor
US Department of Veterans Affairs
1. Study Identification
Unique Protocol Identification Number
NCT00334217
Brief Title
Cognitive Remediation in Early Substance Abuse Treatment
Official Title
Cognitive Remediation in the Initial Phase of Substance Abuse Treatment: Feasibility and Efficacy
Study Type
Interventional
2. Study Status
Record Verification Date
June 2009
Overall Recruitment Status
Terminated
Why Stopped
The intervention could not be successfully carried out in the SADP setting because of issues independent of the cognitive training intervention.
Study Start Date
August 2005 (undefined)
Primary Completion Date
August 2007 (Actual)
Study Completion Date
December 2008 (Actual)
3. Sponsor/Collaborators
Name of the Sponsor
US Department of Veterans Affairs
4. Oversight
5. Study Description
Brief Summary
This study is for the purpose of determining whether cognitive remediation may improve cognition and treatment response in patients entering substance abuse day treatment
Detailed Description
Background: Patients entering substance abuse treatment display cognitive deficits that may reduce their ability to benefit from their treatment. While there is considerable variety in the severity and types of cognitive impairment found in newly recovering patients, problems with attention, memory and executive function are very common. Since treatment requires sustained attention, remembering what is learned, integrating that knowledge and applying it to recovery, impairment in underlying cognitive processes makes successful treatment less likely. Although cognitive functioning improves with sustained sobriety, it is during the early phase of recovery that most patients receive the most intensive treatment. Recent research has suggested that cognitive remediation exercises during this early phase may speed up the return of cognitive functioning and in so doing may have a direct effect on whether patients find the treatment useful and complete their treatment. By keeping patients in treatment longer, cognitive remediation may have an indirect effect on substance abuse outcomes.
Objectives: To pilot test the introduction of cognitive remediation at the Substance Abuse Day Treatment Program (SADP) at the Errara Community Care Center. Aims are 1) to assess the receptivity of patients to the intervention by determining rates of agreement to participate, 2) to determine the number of cognitive remediation sessions that patients are willing to engage in, 3) to assess a variety of cognitive remediation tasks for their acceptability, 4) to evaluate neuropsychological improvements using pre-post assessment, 5) to evaluate its effects on substance abuse treatment participation, and 6) to evaluate its effects on substance abuse outcomes at 6 months follow-up.
Design: Randomized clinical trial of cognitive remediation with an active control condition with observations at baseline, end of treatment and 6-months from intake
6. Conditions and Keywords
Primary Disease or Condition Being Studied in the Trial, or the Focus of the Study
Substance-Related Disorders
Keywords
Psychology: cognitive aspects, Substance-Related Disorders, treatment efficacy
7. Study Design
Primary Purpose
Treatment
Study Phase
Not Applicable
Interventional Study Model
Parallel Assignment
Masking
None (Open Label)
Allocation
Randomized
Enrollment
40 (Anticipated)
8. Arms, Groups, and Interventions
Arm Title
1
Arm Type
Experimental
Arm Description
PSS CogRehab exercises
Arm Title
2
Arm Type
No Intervention
Arm Description
On-line computer games
Intervention Type
Behavioral
Intervention Name(s)
Cognitive Remediation
Intervention Description
PSS Cogrehab
Primary Outcome Measure Information:
Title
Cognitive improvement and adherence to substance abuse treatment
Time Frame
6 month follow-up
10. Eligibility
Sex
All
Accepts Healthy Volunteers
No
Eligibility Criteria
Inclusion Criteria:
Veterans participating in a substance abuse day treatment program at the Errara Community Center
Exclusion Criteria:
Overall Study Officials:
First Name & Middle Initial & Last Name & Degree
Morris D Bell, PhD
Organizational Affiliation
VA Connecticut Health Care System (West Haven)
Official's Role
Principal Investigator
Facility Information:
Facility Name
VA Connecticut Health Care System (West Haven)
City
West Haven
State/Province
Connecticut
ZIP/Postal Code
06516
Country
United States
12. IPD Sharing Statement
Citations:
PubMed Identifier
10397417
Citation
Horner MD, Harvey RT, Denier CA. Self-report and objective measures of cognitive deficit in patients entering substance abuse treatment. Psychiatry Res. 1999 May 31;86(2):155-61. doi: 10.1016/s0165-1781(99)00031-1.
Results Reference
result
PubMed Identifier
12201382
Citation
Teichner G, Horner MD, Roitzsch JC, Herron J, Thevos A. Substance abuse treatment outcomes for cognitively impaired and intact outpatients. Addict Behav. 2002 Sep-Oct;27(5):751-63. doi: 10.1016/s0306-4603(01)00207-6.
Results Reference
result
PubMed Identifier
15301637
Citation
Grohman K, Fals-Stewart W. The detection of cognitive impairment among substance-abusing patients: the accuracy of the neuropsychological assessment battery-screening module. Exp Clin Psychopharmacol. 2004 Aug;12(3):200-7. doi: 10.1037/1064-1297.12.3.200.
Results Reference
result
PubMed Identifier
1562011
Citation
O'Malley S, Adamse M, Heaton RK, Gawin FH. Neuropsychological impairment in chronic cocaine abusers. Am J Drug Alcohol Abuse. 1992;18(2):131-44. doi: 10.3109/00952999208992826.
Results Reference
result
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Cognitive Remediation in Early Substance Abuse Treatment
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