MK0354 Clinical Efficacy and Tolerability Study (0354-004)

Inclusion Criteria: Patient is between 18 and 75 years of age You have taken a statin or other lipid modifying therapy in the last 6-8 weeks You have lipid lab values outside of the range specified in the protocol Exclusion Criteria: Patient is a woman who is pregnant or nursing a child Patient is a woman who is taking hormonal birth-control You are a woman who is planning to donate eggs during the study You plan to give blood during the study or have given within the last 8 weeks You are a woman who is having menopausal hot flashes or are taking medications to prevent menopausal hot flashes You have a known intolerance to or you are allergic to niacin You have any of the following medical conditions: Poorly controlled or newly diagnosed diabetes (within the last 3 months) Thyroid disease (hypothyroidism or hyperthyroidism) A history of stroke, heart attack, coronary bypass surgery, angioplasty, unstable angina or similar heart and artery procedures in the past 3 months History of hemorrhagic stroke or other non-traumatic hemorrhage Peptic ulcer disease in the last 3 months An occurrence of gout within the last year and you are not currently taking allopurinol Cancer (except for successfully treated skin cancer) HIV positive You have a history of drug/alcohol abuse within the last year You consume more than 2 drinks of alcohol per day You do not have access to a telephone You take medications that are not allowed in this study. The study doctor or staff will discuss this with you. Patient has participated in a study with an investigational drug within the last 30 days