A Study of the Immunogenicity and Safety of the 2006-2007 Influenza Vaccine

Inclusion Criteria: Aged at least 18 years on the day of inclusion Informed consent form signed Able to attend all scheduled visits and to comply with all trial procedures For a woman, inability to bear a child or negative urine pregnancy test at Visit 1 For a woman of child-bearing potential: use of an effective method of contraception or abstinence for at least four weeks prior to vaccination and at least three weeks after vaccination. Exclusion Criteria: Febrile illness (oral temperature >=37.5°C) on the day of vaccination Breast-feeding Participation in another clinical trial in the four weeks preceding the trial vaccination Planned participation in another clinical trial during the present trial period Congenital or acquired immunodeficiency, immunosuppressive therapy such as anti-cancer chemotherapy or radiation therapy within the preceding six months, or long-term systemic corticosteroids therapy Systemic hypersensitivity to egg proteins, chick proteins, or to any of the vaccine components, or history of a life-threatening reaction to the trial vaccine or a vaccine containing the same substances Chronic illness at a stage that could interfere with trial conduct or completion Current abuse of alcohol or drug addiction that may interfere with the subject's ability to comply with trial procedures Blood or blood-derived products received in the past three months Any vaccination in the four weeks preceding the trial vaccination Vaccination planned in the three weeks following the trial vaccination Vaccination against influenza in the previous six months Thrombocytopenia or bleeding disorder contraindicating intramuscular vaccination Subject deprived of freedom by an administrative or court order, or in an emergency setting, or hospitalized without his/her consent