Autologous ex Vivo Conjunctival Epithelial Cell Expansion for Ocular Surface Transplantation
Pterygium, Ocular Surface Disease, Stevens Johnson Syndrome
About this trial
This is an interventional treatment trial for Pterygium focused on measuring Culture, Conjunctiva, transplantation, pterygium, ocular surface
Eligibility Criteria
Inclusion Criteria: Patients with ocular surface disorders, e.g. primary pterygium, scheduled for elective surgical excision Indications for surgery will be the presence of ocular surface symptoms in the affected eye, loss of visual acuity from visual axis obscuration or irregular astigmatism, or cosmesis. Only one eye of a patient will be eligible for study entry. Patients who are adult males and females who are aged 21 or older, and are considered mentally sound Patients who are willing to undergo long-term follow-up, as outlined in this protocol Patients who have signed an informed consent form that has been approved by the SNEC Ethics Committee. Exclusion Criteria: Patients less than 21 years of age Patients who are incapable, either by law or of mental state, of giving consent in their own right Patients who are either unable or unwilling to keep scheduled appointments and adhere to the other aspects of the protocol Patients who are pregnant or breastfeeding Patients with a history of drug allergy Patients who have received an investigational drug within 28 days preceding surgery Patients with intraocular pressure over 21 mmHg or history of ocular hypertension or glaucoma Patients who are documented to be steroid responders
Sites / Locations
- Singapore National Eye Centre