Polyvinylpyrrolidone-Sodium Hyaluronate Gel in Reducing Pain From Oral Mucositis in Young Patients With Cancer
Brain and Central Nervous System Tumors, Chordoma, Kidney Cancer
About this trial
This is an interventional supportive care trial for Brain and Central Nervous System Tumors focused on measuring unspecified childhood solid tumor, protocol specific, pain, childhood acute lymphoblastic leukemia, childhood Hodgkin lymphoma, chondrosarcoma, osteosarcoma, childhood soft tissue sarcoma, Wilms tumor and other childhood kidney tumors, neuroblastoma, childhood acute myeloid leukemia/other myeloid malignancies, childhood large cell lymphoma, childhood lymphoblastic lymphoma, childhood small noncleaved cell lymphoma, childhood rhabdomyosarcoma, childhood brain stem glioma, childhood central nervous system germ cell tumor, childhood cerebellar astrocytoma, childhood cerebral astrocytoma/malignant glioma, childhood choroid plexus tumor, childhood craniopharyngioma, childhood ependymoma, childhood medulloblastoma, childhood meningioma, childhood oligodendroglioma, childhood atypical teratoid/rhabdoid tumor, childhood spinal cord neoplasm, childhood supratentorial primitive neuroectodermal tumor, childhood visual pathway and hypothalamic glioma, chordoma, mucositis, Ewing sarcoma/peripheral primitive neuroectodermal tumor (PNET)
Eligibility Criteria
DISEASE CHARACTERISTICS: Diagnosis of cancer, including, but not limited to, the following: Acute lymphoblastic leukemia Acute myeloid leukemia Brain tumor Hodgkin's lymphoma Non-Hodgkin's lymphoma Sarcoma Wilms' tumor Neuroblastoma Meets 1 of the following criteria: Admitted to an in-patient unit after undergoing chemotherapy that is anticipated to cause oral mucositis Admitted to an in-patient unit after undergoing myeloablative therapy followed by peripheral blood stem cell or bone marrow transplantation Is experiencing oral pain due to mucositis PATIENT CHARACTERISTICS: No known hypersensitivity to polyvinylpyrrolidone-sodium hyaluronate gel PRIOR CONCURRENT THERAPY: See Disease Characteristics Concurrent analgesics allowed
Sites / Locations
- Our Lady's Hospital for Sick Children Crumlin
- Birmingham Children's Hospital
- Institute of Child Health at University of Bristol
- Addenbrooke's Hospital
- Leeds Cancer Centre at St. James's University Hospital
- Leicester Royal Infirmary
- Royal Liverpool Children's Hospital, Alder Hey
- Middlesex Hospital
- Great Ormond Street Hospital for Children
- Royal Manchester Children's Hospital
- Sir James Spence Institute of Child Health at Royal Victoria Infirmary
- Queen's Medical Centre
- Oxford Radcliffe Hospital
- Children's Hospital - Sheffield
- Southampton General Hospital
- Royal Marsden - Surrey
- Royal Belfast Hospital for Sick Children
- Royal Aberdeen Children's Hospital
- Royal Hospital for Sick Children
- Royal Hospital for Sick Children
- Childrens Hospital for Wales