WENBIT - Western Norway B Vitamin Intervention Trial (WENBIT)
Coronary Artery Disease, Myocardial Infarction, Cerebrovascular Stroke
About this trial
This is an interventional prevention trial for Coronary Artery Disease focused on measuring Coronary Artery Disease, Myocardial Infarction, Cerebrovascular Stroke, Homocysteine, Folic Acid, Vitamin B 12, Vitamin B 6
Eligibility Criteria
Inclusion Criteria: adults ≥ 18 years able to give informed consent patients prepared to undergo long-term follow-up patients with and without significant coronary artery disease (CAD) who have undergone coronary angiography just before inclusion Exclusion Criteria: patients who are not available for follow-up patients who have previously participated in this study patients with known alcohol abuse or serious mental illness patients with known active malignant disease patients who have undergone coronary angiography for specific reasons, i.e. assessment for cardiac transplantation, kidney donor, heart donor, diagnostic assessment of cardiomyopathy
Sites / Locations
- Department of Heart Disease, Haukeland University Hospital
- Department of Cardiology, Stavanger University Hospital
Arms of the Study
Arm 1
Arm 2
Arm 3
Arm 4
Active Comparator
Active Comparator
Active Comparator
Placebo Comparator
1
2
3
4
folic acid (0.8 mg) plus vitamin B12 (0.4 mg) and vitamin B6 (40 mg)
folic acid (0.8 mg) plus vitamin B12 (0.4 mg)
vitamin B6 (40 mg)
placebo