Efficacy of T1675 Versus Placebo in Patients With Bilateral Treated Moderate Dry Eye Syndrome

Inclusion Criteria: Signed and dated informed consent. Male or female aged from 18 to 90 years old. Known treated bilateral dry eye. Dry eye syndrome confirmed by ocular examination with a fluorescein and/or lissamine green staining, BUT and Schirmer, performed within the last 12 months before Inclusion Visit, for both eyes. Bilateral symptomatology suggestive of dry eye defined by: at least one of the following ocular symptoms suggestive of dry eye (burning, stinging, dryness feeling, sandy and/or gritty sensation, light sensitivity, reflex tearing, ocular fatigue) and Questioning on patient's feeling (score >=3). Fulfilling the following criteria of dry eye syndrome in both eyes defined by: Keratoconjunctivitis defined by a lissamine green score ≥ 4 (Van Bijsterveld score) and Schirmer test <= 10 mm in 5 min or BUT < 10 s Exclusion Criteria: severe dry eye symptom eyelid dysfunction severe progressive rosacea any relevant ocular anomaly interfering with ocular surface best corrected far visual acuity <= 1/10 history of ocular allergy traumatism, infection, inflammation within last 3 months ocular surgery and laser within the last 3 months lasik, laser, PKR within the last 12 months contact lenses any concomitant nutritive supplementation, vitamins any topical concomitant treatment