Comparison of Two Different Medications Used to Treat Elevated Intracranial Pressure
Increased Intracranial Pressure
About this trial
This is an interventional treatment trial for Increased Intracranial Pressure
Eligibility Criteria
Inclusion Criteria: Documented SAH (by computed tomography or lumbar puncture), ICH, TBI or brain tumor Patient greater than or equal to 18 years of age ICP monitor in place ICP greater than 20mmHg, not related to a transient noxious stimulus and not responding to standard measures for controlling ICP (ventricular drainage, elevation of head of the bed and optimizing PaCO2) Patient or patient's legally authorized representative has provided written informed consent Exclusion Criteria: Patient less than 18 years of age Lack of ICP monitoring Patient received Mannitol prior to placement of ICP monitor Baseline serum osmolarity of greater than 310 mOsm/L Patient is currently enrolled in another investigational drug or device study Congestive heart failure at time of enrollment Chronic renal failure on hemodialysis Pregnancy